Results 81 to 90 of about 13,295,690 (363)

Infectious Skin Diseases in Children in General Practice: epidemiology and management [PDF]

open access: yes, 2007
The increasing proportion of skin diseases, especially infectious and allergic skin diseases, encountered in general practice represents a substantial part of the morbidity in children.
Mohammedamin, R.S.A. (Robbert)
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

open access: yes, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J   +33 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

The burden of skin and subcutaneous diseases: findings from the global burden of disease study 2019

open access: yesFrontiers in Public Health, 2023
Background The small number of existing integrative studies on the global distribution and burden of all types of skin and subcutaneous diseases hinders relevant comparisons.
Aobuliaximu Yakupu   +8 more
semanticscholar   +1 more source

Stem cells conditioned medium: a new approach to skin wound healing management [PDF]

open access: yes, 2014
Stem cell biology has gained remarkable interest in recent years, driven by the hope of finding cures for numerous diseases including skin wound healing through transplantation medicine.
Govindasamy, V.   +4 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The Experience of Use General Air Cryotherapy for Correction of Psoriasis

open access: yesМедицинский вестник Юга России, 2012
Purpose: We investigated the efficacy and safety of general air cryotherapy with addition of the moisturizing agent Xemose cream (Uriage cosmetic line) for correction of psoriasis.
Ya. Yu. Solonchenko   +2 more
doaj  

A new gender-specific model for skin autofluorescence risk stratification [PDF]

open access: yes, 2015
Advanced glycation endproducts (AGEs) are believed to play a significant role in the pathophysiology of a variety of diseases including diabetes and cardiovascular diseases.
Ahmad, MS   +4 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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