Results 91 to 100 of about 12,686,302 (306)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Visual Signs of Chronic Diffuse Liver Diseases: the Stigma of Skin, its Appendages and Mucous Membranes

open access: yes, 2013
Introduction. The condition of the skin has always been a reflection of the state of the internal organs, in particular, organs of the gastrointestinal system, liver.
Abrahamovych O.   +2 more
core   +1 more source

Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases

open access: yesFrontiers in Immunology, 2019
Tyrosine kinases relay signals from diverse leukocyte antigen receptors, innate immune receptors, and cytokine receptors, and therefore mediate the recruitment and activation of various leukocyte populations. Non-receptor tyrosine kinases of the Jak, Src,
K. Szilveszter, T. Németh, A. Mócsai
semanticscholar   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Skin diseases among elderly inhabitants of Bialystok, Poland

open access: yes, 2015
Mateusz Cybulski, Elzbieta Krajewska-Kulak Department of Integrated Medical Care, Faculty of Health Sciences, Medical University of Bialystok, Bialystok, Poland Purpose: The aim of the study was to assess the most frequent skin diseases in people over ...
Cybulski M, Krajewska-Kulak E
core  

Non-invasive methods and assessment of skin diseases.

open access: yes, 2006
description of non-inasive methods evaluating skin diseases, such as psoriasis and atopic ...
SEIDENARI, Stefania   +5 more
core   +1 more source

Gender aspects in skin diseases. [PDF]

open access: yes, 2010
Gender differences in medicine have been recognized in anatomy, physiology, as well as in epidemiology and manifestations of various diseases. With respect to skin disorders, males are generally more commonly afflicted with infectious diseases while ...
Chen, W;Mempel, M;Traidl-Hofmann, C;Al Khusaei, S;Ring, J
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

The role of interleukin 16 in the pathogenesis of selected skin diseases

open access: yes, 2014
Interleukin-16 (IL-16) is a proinflammatory cytokine with a pleiotropic impact on cells of the immune system. Based on its biological properties including activation of CD4+ T cell migration and proliferation and also stimulation of proinflammatory ...
Michał Żmijewski   +5 more
core   +1 more source

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