Results 91 to 100 of about 13,295,690 (363)

Intestinal microbiota influences non-intestinal related autoimmune diseases [PDF]

, 2018
Indexación: Scopus.The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner.
Bonifaz, L.C., Boudin, H., Bueno, S.M., Coronado-Arrázola, I., Kalergis, A.M., Neunlist, M., Opazo, M.C., Ortega-Rocha, E.M., Riedel, C.A.   +8 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The High Prevalence of Skin Diseases in Adults Aged 70 and Older

Journal of The American Geriatrics Society, 2020
To determine the prevalence of skin findings and skin diseases in adults aged 70 and older, and to study the association between cutaneous diseases and socioeconomic status (SES), sex, and living status in the older population.
S. Sinikumpu, J. Jokelainen, A. K. Haarala, Maija-Helena Keränen, S. Keinänen-Kiukaanniemi, L. Huilaja   +5 more
semanticscholar   +1 more source

In Silico Approaches and the Role of Ontologies in Aging Research [PDF]

, 2013
The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means.
Busch, Hauke, Börries, Melanie, de Grey, Aubrey, Fuellen, Georg, Hahn, Udo, Hiller, Thomas, Hoeflich, Andreas, Jansen, Ludger, Janssens, Georges E., Kaleta, Christoph, Meinema, Anne C., Others, Schofield, Paul N., Schäuble, Sascha, Smith, Barry   +14 more
core  

Effects of air pollution and meteorological parameters on human health in the city of Athens, Greece [PDF]

, 2010
The impact of air pollution (CO, NO, NO2, SO2, O3) and meteorological parameters (air temperature, humidity and atmospheric pressure) on three indicators of human morbidity (circulatory, respiratory and skin diseases) is quantified, while the sensitivity
Akaike, Anderson, Bell, Box, Braat, Braga, Brunekreef, Burnett, Cho, Curriero, Davidson, Desqueyroux, Dockery, Dominici, Doriana Delfino, Emmanouil Mentzakis, Forster, Goldberg, Haines, Hastie, Hong, International, Jamason, Kalkstein, Kalkstein, Katsouyanni, Katsouyianni, Katsouyianni, Katsouyianni, Katsouyianni, Laschewski, Le Tertre, Linn, Mar, Martens, McCullagh, McGeehin, Pattenden, Patz, Polosa, Saez, Schwartz, Schwartz, Schwartz, Schwartz, Smith, Sunyer, Touloumi, Wooldridge   +48 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Psychosocial impact of skin diseases: A population-based study

PLoS ONE, 2020
Background While it is well established that skin disease places significant psychosocial burden on a patient’s wellbeing, its effects have rarely been examined in Asian populations.
Y. Yew, A. Kuan, Lixia Ge, C. Yap, B. Heng   +4 more
semanticscholar   +1 more source

The Clinical Spectrum of Rare Inherited Ichthyosis in China: A Review of Thirty-five Cases

Acta Dermato-Venereologica
Inherited ichthyosis comprises a spectrum of genetic disorders related to over 50 pathogenic genes. However, there are limited data summarizing the clinical and molecular characteristics of Chinese patients.
Ruiyu Xiang, Xin Huang, Yihe Liu, Shuya Sun, Di Hua, Ran Mo, Yong Yang, Zhiming Chen   +7 more
doaj   +1 more source

High Glucosinolate Mustard and Potato Trial [PDF]

, 2013
High glucosinolate mustard (HGM) can be planted as a cover crop to suppress weeds and disease. Studies have shown a reduction in soil-borne diseases, as well as advantages in mitigating weed pressure, after planting HGM cover crops.
Cummings, Erica, Darby, Heather, Harwood, Hannah, Monahan, Susan   +3 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source