A Comprehensive Review of the Strategies to Reduce Retinoid-Induced Skin Irritation in Topical Formulation [PDF]
Dermatology Research and PracticeCurrently, retinoids are known for their abundant benefits to skin health, ranging from reducing signs of aging and decreasing hyperpigmentation to treating acne. However, it cannot be denied that there are various side effects associated with the use of
Angga Cipta Narsa +5 more
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Evaluation of Skin Irritation of Acids Commonly Used in Cleaners in 3D-Reconstructed Human Epidermis Model, KeraSkinTM [PDF]
Toxics, 2022 Cleaners such as dishwashing liquids contain various chemicals that cause skin damage. Alkaline agents used in cleaners alter the lipid composition of the skin and damage the skin barrier.
Jee-hyun Hwang +4 more
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Skin irritation in children undergoing orthodontic facemask therapy [PDF]
Scientific Reports, 2023 Orthodontic facemasks are extraoral orthodontic appliances that influence maxillary and mandibular development in children with skeletal Class III malocclusion.
Harim Kim +5 more
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Improved Tool for Predicting Skin Irritation on Reconstructed Human Epidermis Models Based on Electrochemical Impedance Spectroscopy [PDF]
Biosensors, 2023 The rabbit skin irritation test has been the standard for evaluating the irritation potential of chemicals; however, alternative methods that do not use animal testing are actively encouraged.
Manuel Chacón +8 more
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Protecting your skin: a highly accurate LSTM network integrating conjoint features for predicting chemical-induced skin irritation [PDF]
Journal of CheminformaticsSkin irritation is a significant adverse effect associated with chemicals and drug substances. Quantitative structure-activity relationship (QSAR) is an alternative method bypassing in vivo assay for filling data gaps in chemical risk assessment. In this
Huynh Anh Duy, Tarapong Srisongkram
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Specific barrier response profiles after experimentally induced skin irritation in vivo. [PDF]
Contact Dermatitis, 2018 Recently, natural moisturizing factors (NMFs) and corneocyte surface topography were suggested as biomarkers for irritant dermatitis.
Soltanipoor M +8 more
europepmc +4 more sources
Phytochemical analysis and evaluation of skin irritation, acute and sub-acute toxicity of Cymbopogon citratus essential oil in mice and rabbits [PDF]
Toxicology Reports, 2019 Cymbopogon citratus has been used by the local people in Ankober district, northern Ethiopia, as traditional medicine to treat various ailments. Its essential oil has been shown to have antibacterial, antifungal, antiprotozoal, anti-carcinogenic, anti ...
Ermias Lulekal +9 more
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Topical Microemulsions: Skin Irritation Potential and Anti-Inflammatory Effects of Herbal Substances. [PDF]
Pharmaceuticals (Basel), 2023 Microemulsions (MEs) have gained prominence as effective drug delivery systems owing to their optical transparency, low viscosity, and thermodynamic stability.
Leanpolchareanchai J +1 more
europepmc +2 more sources
Antiaging and Skin Irritation Potential of Four Main Indonesian Essential Oils
Cosmetics, 2021 Essential oils possess antiaging properties due to their antioxidant activity. This study aims to determine the antiaging activities of four main Indonesian essential oils and their irritation potential on the skin.
Dwinna Rahmi +6 more
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ChemSkin Reference Chemical Database for the Development of an In Vitro Skin Irritation Test. [PDF]
Toxics, 2021 Since the animal test ban on cosmetics in the EU in 2013, alternative in vitro safety tests have been actively researched to replace in vivo animal tests.
Han J, Lee GY, Bae G, Kang MJ, Lim KM.
europepmc +2 more sources