Low friction layer in sanitary products for reduced skin irritation [PDF]
Scientific ReportsSanitary napkins are essential during menstruation, but they can sometimes cause skin irritation due to friction. In this study, we propose a novel design: introducing a low-friction layer within the bulk of a sanitary napkin.
Toshiaki Nishi +5 more
doaj +2 more sources
Skin irritation in children undergoing orthodontic facemask therapy [PDF]
Scientific Reports, 2023 Orthodontic facemasks are extraoral orthodontic appliances that influence maxillary and mandibular development in children with skeletal Class III malocclusion.
Harim Kim +5 more
doaj +2 more sources
Evaluation of Skin Irritation of Acids Commonly Used in Cleaners in 3D-Reconstructed Human Epidermis Model, KeraSkinTM [PDF]
Toxics, 2022 Cleaners such as dishwashing liquids contain various chemicals that cause skin damage. Alkaline agents used in cleaners alter the lipid composition of the skin and damage the skin barrier.
Jee-hyun Hwang +4 more
doaj +2 more sources
Skin evaluation of turmeric/epigallocatechin-3-gallate emulgel for skin irritation and sensitisation effects in healthy Thai participants (TULIP): a protocol for a randomised, double-blind, placebo-controlled trial [PDF]
BMJ OpenBackground Evaluating skin reactions is crucial in topical product development. Turmeric/epigallocatechin-3-gallate (EGCG) emulgel demonstrates therapeutic potential for cutaneous diseases, warranting further investigation in human studies.
Ajaree Rayanakorn +6 more
doaj +2 more sources
A Comprehensive Review of the Strategies to Reduce Retinoid-Induced Skin Irritation in Topical Formulation [PDF]
Dermatology Research and PracticeCurrently, retinoids are known for their abundant benefits to skin health, ranging from reducing signs of aging and decreasing hyperpigmentation to treating acne. However, it cannot be denied that there are various side effects associated with the use of
Angga Cipta Narsa +5 more
doaj +2 more sources
A Study on the Skin Irritation Toxicity Test of Processed Sulfur in New Zealand White Rabbit [PDF]
Journal of Pharmacopuncture, 2022 Objectives: This study was performed to evaluate the skin irritation toxicity of processed sulfur. Methods: All experiments were conducted at Medvill (Korea), an institution authorized to perform non-clinical studies, under the Good Laboratory Practice ...
Hoseok Jung +4 more
doaj +2 more sources
Skin irritation testing using human iPSCs derived 3D skin equivalent model. [PDF]
PLoS ONEArtificial skin models have emerged as valuable tools for evaluating cosmetic ingredients and developing treatments for skin regeneration. Among them, 3D skin equivalent models (SKEs) using human primary skin cells are widely utilized and supported by ...
Hyewon Shin +16 more
doaj +2 more sources
Improved Tool for Predicting Skin Irritation on Reconstructed Human Epidermis Models Based on Electrochemical Impedance Spectroscopy [PDF]
Biosensors, 2023 The rabbit skin irritation test has been the standard for evaluating the irritation potential of chemicals; however, alternative methods that do not use animal testing are actively encouraged.
Manuel Chacón +8 more
doaj +2 more sources
Skin corrosion and irritation test of sunscreen nanoparticles using reconstructed 3D human skin model [PDF]
Environmental Health and Toxicology, 2014 Objectives Effects of nanoparticles including zinc oxide nanoparticles, titanium oxide nanoparticles, and their mixtures on skin corrosion and irritation were investigated by using in vitro 3D human skin models (KeraSkinTM) and the results were compared ...
Jonghye Choi +5 more
doaj +3 more sources
Alternatives to Laboratory Animals, 2009 A skin irritation test (SIT) utilising a common protocol for two in vitro reconstructed human epidermal (RhE) models, EPISKIN® and EpiDerm™, was developed, optimised and evaluated as a replacement for the in vivo rabbit skin irritation test in an ECVAM-sponsored validation study.
Paul Kearney +5 more
openaire +4 more sources