Results 91 to 100 of about 948,428 (252)
Lidocaine permeation from a lidocaine NaCMC:gel microgel formulation in microneedle pierced skin: vertical (depth averaged) and horizontal permeation profiles [PDF]
, 2015 Common local anaesthetics such as lidocaine are administered by the hypodermic parenteral route but it causes pain or anxiety to patients. Alternatively, an ointment formulation may be applied which involves a slow drug diffusion process.
Atul Nayak (1253046) +2 more
core +3 more sources
Combined approach of nanoemulgel and microneedle pre-treatment as a topical anticellulite therapy
ADMET and DMPKBackground and purpose: Cellulite is caused by changes in the metabolism of the fatty tissue beneath the skin. Methylxanthines and retinoids are commonly added to the different anticellulite products. However, their topical permeation into the dermis is
Hiba Imad Hameed +1 more
doaj +1 more source
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2019 The assessment of drug permeation into/across the skin is traditionally accomplished using Franz diffusion cells with subsequent analysis by conventional chromatographic methods such as HPLC and more recently using advanced imaging techniques.
Mohammed Hussain Al-Mayahy +2 more
doaj +1 more source
, 2011 The effective transdermal drug delivery depends on the capability of the formulation to deliver the drug through the skin at the amount adequate to exert desired pharmacological reponse.
ง้าวหิรัญพัฒน์, ธนะเศรษฐ์ +3 more
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Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Skin permeation and metabolism of di(2-ethylhexyl) phthalate (DEHP).
, 2014 Phthalates are suspected to be endocrine disruptors. Di(2-ethylhexyl) phthalate (DEHP) is assumed to have low dermal absorption; however, previous in vitro skin permeation studies have shown large permeation differences.
Gaudin, René +11 more
core +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors
Advanced Science, EarlyView.This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung +7 more
wiley +1 more source
Permeation Enhancers for Enhanced Topical Delivery of Pharmaceutical and Cosmeceutical Products
Journal of Dermatology and Dermatologic SurgeryBackground: Topical cosmetic and therapeutic agents are often limited in their effectiveness due to the skin barrier, which hinders the permeation of active ingredients.
Maha N. Abu Hajleh +5 more
doaj +1 more source
Iontophoresis: Skin Permeation Enhancement and Applications [PDF]
, 2011 Transdermal drug delivery (TDD) systems offer a number of potentialadvantages over conventional methods such as injectable and oraldelivery as they avoid the first pass metabolism and increase thepatient’s compliance.
Ngawhirunpat, Tanasait +1 more
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