Results 81 to 90 of about 948,428 (252)

Effect of plasma surface treatment of poly(dimethylsiloxane) on the permeation of pharmaceutical compounds

Journal of Pharmaceutical Analysis, 2017
This paper addresses the modification of poly(dimethylsiloxane), i.e. PDMS, using plasma surface treatment and a novel application of the membrane created.
Laura J. Waters, Catherine V. Finch, A.K.M. Mehedi H. Bhuiyan, Karl Hemming, John C. Mitchell   +4 more
doaj   +1 more source

In vitro human skin permeation of endoxifen: potential for local transdermal therapy for primary prevention and carcinoma in situ of the breast

, 2011
Oukseub Lee1, David Ivancic1, Robert T Chatterton Jr2, Alfred W Rademaker3, Seema A Khan11Department of Surgery, 2Department of Obstetrics/Gynecology, 3Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL ...
Khan SA, Ivancic D, Lee O, Rademaker AW, Chatterton RT Jr   +4 more
core  

Skin‐Like Tri‐Modal Sensors Based on Soft Piezoelectric and Ionic Composites

Advanced Materials Technologies, EarlyView.
Inspired by the multimodal perception of human skin, a soft, skin‐like tri‐modal sensor is presented. The device incorporates an ionically conductive, piezoelectric, elastic composite as its active layer, enabling independent detection of temperature, static strain, and dynamic strain within a single two‐terminal architecture.
Liren Wang, Peter Zalar, Vishva Bhate, Takeo Furukawa, Hidekazu Kodama, Yijun Liu, Yuanyuan Zhou, Chuang Hou, Siyuan Liu, Naoji Matsuhisa   +9 more
wiley   +1 more source

Usefulness of Low-Resistance Electrodes Used in Iontophoresis to Enhance Skin Permeability of Drugs

Molecules
This study investigated how electrode design and electrical conditions influence iontophoretic transdermal drug delivery. A low-resistance silver electrode (Ag*) was developed to reduce interfacial resistance and improve the delivery of lidocaine ...
Takeshi Oshizaka, Yuya Yanagibashi, Yuki Matsui, Yusaku Kachi, Issei Takeuchi, Kenji Mori, Kenji Sugibayashi   +6 more
doaj   +1 more source

Liquid Crystal Elastomer Actuator Matrix for Large Area Applications

Advanced Materials Technologies, EarlyView.
A scalable approach is used to manufacture a digitally‐controllable, 2D 5 × 5 actuator matrix. The elements of the matrix are produced by direct ink writing of a liquid crystal elastomer ‘artificial muscle’ on large‐area flexible thin‐film heaters. In optimizing the low‐power actuators, multiple heater designs and substrate materials are investigated ...
Giulia Spallanzani, Bart Peeters, Danqing Liu, Peter Zalar, Hylke B. Akkerman, Jeroen A. H. P. Sol   +5 more
wiley   +1 more source

Dependence of skin drug permeation on microstructure and time dependent alterations following application of more-phasic dermatological formulations studied by the continuous phase drug concentration concept [PDF]

, 2006
In this work, the dependence of transdermal delivery of hydrophilic drugs on mass fraction and microstructure of dispersed phase of multi-phase dermatological o/w formulations was studied.
Nalenz, Heiko
core   +1 more source

3D Printing of Self‐Healing Polymers by Material Extrusion: A Process‐Centric Review of Setups, Parameters, and Applications

Advanced Robotics Research, EarlyView.
This review highlights recent advances in material extrusion 3D printing of self‐healing polymers, focusing on the interplay between material chemistry, rheology, hardware customization, and process optimization. Filament‐ and ink‐based extrusion strategies, multimaterial architectures, and postprocessing approaches are discussed for applications in ...
Antonio Pavone, Gianni Stano, Gianluca Percoco   +2 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Iontophoresis-Mediated Transdermal Permeation of Peptide Dendrimers across Human Epidermis

, 2013
Purpose of the Study: The overall aim of the present work was to elucidate the effects of iontophoresis on assisting permeation/deposition of peptide dendrimers across/within human skin.
Parekh, H. S., Mutalik, S, Parekh, HS, Roberts, M. S., Anissimov, YG, Grice, JE, Grice, J. E., Roberts, MS, Anissimov, Y. G., Mutalik, S.   +9 more
core   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source