Results 171 to 180 of about 31,339 (306)

Decoding Tattoo and Permanent Makeup Pigments: Linking Physicochemical Properties to Absorption, Distribution, Metabolism, and Elimination Profiles Using Quantitative Structure–Activity Relationship (QSAR)‐Based New Approach Methodologies (NAMs)

Advanced Intelligent Discovery, EarlyView.
This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod, Ajay Vikram Singh, Preeti Bhardwaj, Tulika Rai, Sweta Vijay Nakhale, Amruta Shelar, Rajendra Patil, Peter Laux, Andreas Luch, Christopher J. Osgood, Michael W. Stacey   +10 more
wiley   +1 more source

Scalable microfluidic fabrication of optimized phospholipid nanocarriers for enhanced topical bioavailability: Analytical QbD integration and <i>ex vivo</i> skin permeation assessment. [PDF]

Int J Pharm X
Bucciarelli G, Curzi G, Tiboni M, Aluigi A, Heinz A, Casettari L.   +5 more
europepmc   +1 more source

Smart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications

Advanced Intelligent Discovery, EarlyView.
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang, Ming Dong, Rongrong Bao, Caofeng Pan   +3 more
wiley   +1 more source

Keratin-Functionalized Transfersomes for Improving the Skin Permeation and Deposition of Podophyllotoxin. [PDF]

ACS Omega
Niu J, Yuan M, Wang L, Zhang P, Cui X, Fan Y, Liu X, Wang J.   +7 more
europepmc   +1 more source

The “weight” of skin structure and lipidomics on percutaneous absorption of xenobiotics

, 2017
Molecules can successfully penetrate and permeate skin barrier in relation to their physicochemical characteristics, such as partition coefficient and molecular weight.
A. Casiraghi, M. Orioli
core  

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Development of an Antimicrobial Nanoemulsion Based on <i>Cordia verbenacea</i> Essential Oil: Properties, Stability, Irritability, and In Vitro Skin Permeation. [PDF]

Pharmaceutics
da Silva FS, Matos BN, Dos Santos RD, Amaral VA, Araújo MO, do Prado BA, Martins CM, da Camara CAG, de Moraes MM, Dias DJS, Cardoso CO, Sá Barreto LCL, Rodrigues da Silva IC, Orsi DC, Gelfuso GM.   +14 more
europepmc   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

A Dissolving Microneedle Design for Poorly Water-Soluble Drugs for Enhanced Skin Permeation and Transdermal Delivery Fabricated Using 3D Printing. [PDF]

Micromachines (Basel)
Jin SG.
europepmc   +1 more source

Design‐for‐Benchmarking in Soft Robotics: Navigating Component‐System Dichotomy

Advanced Intelligent Systems, EarlyView.
Soft robotics faces a profound evaluation challenge: the Component‐System Dichotomy, where isolated component tests fail to predict integrated performance. This article presents a systematic survey of critical reporting gaps across actuation, sensing, and control.
Matteo Lo Preti, Muhammad Sunny Nazeer, Josh Pinskier, David Howard, Cecilia Laschi   +4 more
wiley   +1 more source