Results 41 to 50 of about 62,571 (334)

Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid [PDF]

, 2017
BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice.
A Loeffler, A Loeffler, Anette Loeffler, BK Valentine, D Bommannan, DH Lloyd, DH Lloyd, DH Lloyd, DJ Davies, G Stuttgen, GH Nesbitt, H Löffler, I Degim, IS Mason, JD Bos, JF Summers, Jo Larner, JT Headington, K Brain, KM Credille, LA Ahlstrom, LA Ahlstrom, LE Berrutti, MA Cobb, NA Monteiro-Riviere, PM Elias, Ross Bond, RS Mueller, Sian-Marie Frosini, SM Clark   +29 more
core   +4 more sources

Evaluation of percutaneous permeation of repellent DEET and sunscreen oxybenzone from emulsion-based formulations in artificial membrane and human skin

Acta Pharmaceutica Sinica B, 2014
Insect repellent DEET and sunscreen ingredient oxybenzone play an essential role in minimizing vector-borne diseases and skin cancers. The purpose of this study was to investigate the effects of emulsion type, addition of thickening agent and droplet ...
Tao Wang, Donald Miller, Frank Burczynski, Xiaochen Gu   +3 more
doaj   +1 more source

Transdermal evaluation of caffeine in different formulations and excipients [PDF]

, 2013
Background: The stratum corneum(SC) forms adifficultphysical barrier fordrugs to pass through the skin. Several strategieswere developed to overcome this barrier.Optimization of topical drug formulations by selected excipients may facilitate the ...
Boonen, Jente, Burvenich, Christian, De Spiegeleer, Bart, Mehuys, Els, Peremans, Kathelijne, Remon, Jean Paul, Roche, Nathalie, Veryser, Lieselotte   +7 more
core   +2 more sources

Hydrogel increases diclofenac skin permeation and absorption [PDF]

Biopharmaceutics & Drug Disposition, 2019
AbstractPurposeTopical nonsteroidal anti‐inflammatory drug formulations are used commonly to treat musculoskeletal pain and inflammation. Drug properties and formulation composition are the primary determinants of the transdermal drug delivery rate. The ex vivo transdermal flux through human skin of three topical diclofenac formulations was compared ...
Eleonore Haltner‐Ukomadu, Manuel Sacha, Andrea Richter, Khaled Hussein   +3 more
openaire   +3 more sources

The use of heat and chemical penetration enhancers to increase the follicular delivery of erythromycin to the skin [PDF]

, 2019
Copyright © 2019. Published by Elsevier B.V.The effect of heat on the follicular absorption of drugs into the skin has not previously been investigated.
Akomeah, Alberti, Baden, Butcher, Cada, Coldman, Edwards, F. Caserta, FDA, Feldmann, Goh, Higuchi, ICH, Q2(R1), Kim, Kligman, Liu, M.B. Brown, McAuley, McAuley, Minson, Motwani, Motwani, OECD, Oliveira, Otberg, Park, Piazza, Pierard, Rancan, Saar, Santos, Sato, Shergill, Szabo, Teichmann, Toll, Twist, W.J. McAuley, Wood, Wood, Wood, Yarnitsky, Zhang   +42 more
core   +2 more sources

A rationale for the preparation of asymmetric pervaporation membranes [PDF]

, 1985
Pervaporation is carried out primarily with homogeneous membranes. An improvement in permeation rate can be achieved by using asymmetric or composite membranes. In order to maintain a high selectivity, very dense top layers are needed.
Mulder, M.H.V., Oude Hendrikman, J., Smolders, C.A., Wijmans, J.G.   +3 more
core   +2 more sources

Cutaneous Permeation of a Percutaneously Applied Glucocorticoid Using Plant-Based Anionic Phospholipids in Hydrogenated Vegetable Oil: A Preliminary Study

Medicina, 2022
Purpose: It is important that, when corticosteroids are used therapeutically, concentrations be reduced as much as possible to mitigate potential adverse events and side effects.
Jack V. Greiner, Hridaya N. Bhargava, Thomas Glonek, Donald R. Korb, Michael E. Lindsay, Paula J. Oliver   +5 more
doaj   +1 more source

Rapid Screening of Mupirocin Skin Permeation Modification by Micronized and Nanonized Alaptide

ADMET and DMPK, 2014
The investigation deals with the affection of permeation of mupirocin from the Bactroban® Leciva ointment through full-thickness pig ear skin by the original Czech compound (S)-8-methyl-6,9-diazaspiro[4.5]decan-7,10-dione, known under the international ...
Josef Jampilek, Radka Opatrilova
doaj   +1 more source

Liposome–skin interactions and their effects on the skin permeation of drugs

European Journal of Pharmaceutical Sciences, 1999
The aim of the study was to evaluate the interaction of phospholipid liposomes with skin and stratum corneum lipid liposomes (SCLLs). The influence of phospholipid liposomes on the skin permeability of model drugs was also studied. The transdermal flux of the drugs applied in various phospholipid containing formulations through human epidermis was ...
Juha Kiesvaara, Jukka Mönkkönen, Riitta Valjakka-Koskela, Merja Kirjavainen, Arto Urtti   +4 more
openaire   +3 more sources

A Novel Polymer Insect Repellent Conjugate for Extended Release and Decreased Skin Permeation of Para-Menthane-3,8-Diol

Pharmaceutics, 2021
Background: We developed a novel polymer insect repellent conjugate for extended release and decreased skin permeation of the volatile insect repellent p-menthane-3,8-diol (PMD).
Sayyed I. Shah, Vitaliy V. Khutoryanskiy, Adrian C. Williams   +2 more
doaj   +1 more source