Results 41 to 50 of about 1,692,764 (393)
Influence of Lactobacillus Biosurfactants on Skin Permeation of Hydrocortisone
Pharmaceutics, 2021 One of the most widely used strategies to improve drug diffusion through the skin is the use of permeation enhancers. The aim of this work was to investigate the effect of two biosurfactants (BS), produced by Lactobacillus crispatus BC1 and Lactobacillus
Angela Abruzzo +8 more
doaj +1 more source
Transdermal evaluation of caffeine in different formulations and excipients [PDF]
, 2013 Background: The stratum corneum(SC) forms adifficultphysical barrier fordrugs to pass through the skin. Several strategieswere developed to overcome this barrier.Optimization of topical drug formulations by selected excipients may facilitate the ...
Boonen, Jente +7 more
core +2 more sources
Pharmaceutics, 2016 Generally, the blood and skin concentration profiles and steady-state skin concentration of topically applied or exposed chemicals can be calculated from the in vitro skin permeation profile. However, these calculation methods are particularly applicable
Fadli Mohd +4 more
doaj +1 more source
In Vitro Permeation of Micronized and Nanonized Alaptide from Semisolid Formulations
The Scientific World Journal, 2013 This study is focused on in vitro permeation of the original Czech compound, a skin/mucosa tissue regeneration promoter, known under the international nonproprietary name “alaptide,” in micronized and nanonized forms.
Radka Opatrilova +4 more
doaj +1 more source
Microneedle-Assisted Percutaneous Delivery of a Tetramethylpyrazine-Loaded Microemulsion
Molecules, 2017 This study examined the efficacy of the percutaneous delivery of a tetramethylpyrazine-loaded microemulsion (TMP-ME) on skin pretreated with microneedles (MN).
Qiang Zu +4 more
doaj +1 more source
Frontiers in Materials, 2022 Among different topical drug delivery systems, nanoemulsions (NEs) are attractive due to enhanced skin permeation potential and minimum toxicity. Topical nanoemulgels (NEMGELs) contain both gelling agents and NEs and thus can enhance skin permeation with
Soliman Mohammadi-Samani +6 more
doaj +1 more source
Recent developments in skin mimic systems to predict transdermal permeation [PDF]
, 2015 In recent years there has been a drive to create experimental techniques that can facilitate the accurate and precise prediction of transdermal permeation without the use of in vivo studies.
Waters, Laura J.
core +1 more source
Quantitative Structure-Permeation Relationships (QSPeRs) to Predict Skin Permeation: A Critical Evaluation [PDF]
Pharmaceutical Research, 2004 Development of reliable mathematical models to predict skin permeability remains a challenging objective. This article examines some of the existing algorithms and critically evaluates their statistical relevance.Complete statistics were recalculated for a number of published models using a stepwise multiple regression procedure.
Geinoz, Sandrine +3 more
openaire +3 more sources
Enhancement of Skin Delivery of Drugs Using Proposome Depends on Drug Lipophilicity
Pharmaceutics, 2021 The study aims to investigate the propylene glycol-based liposomes named ‘proposomes’ in enhancing skin permeation of drugs with different physicochemical properties. Ibuprofen, tofacitinib citrate, rhodamine B, and lidocaine were loaded into proposomes.
Himanshu Kathuria +7 more
doaj +1 more source
Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core +1 more source