Results 31 to 40 of about 31,339 (306)

Liposome–skin interactions and their effects on the skin permeation of drugs

open access: yesEuropean Journal of Pharmaceutical Sciences, 1999
The aim of the study was to evaluate the interaction of phospholipid liposomes with skin and stratum corneum lipid liposomes (SCLLs). The influence of phospholipid liposomes on the skin permeability of model drugs was also studied. The transdermal flux of the drugs applied in various phospholipid containing formulations through human epidermis was ...
M, Kirjavainen   +4 more
openaire   +2 more sources

In Vitro Permeation of Micronized and Nanonized Alaptide from Semisolid Formulations

open access: yesThe Scientific World Journal, 2013
This study is focused on in vitro permeation of the original Czech compound, a skin/mucosa tissue regeneration promoter, known under the international nonproprietary name “alaptide,” in micronized and nanonized forms.
Radka Opatrilova   +4 more
doaj   +1 more source

Microneedle-Assisted Percutaneous Delivery of a Tetramethylpyrazine-Loaded Microemulsion

open access: yesMolecules, 2017
This study examined the efficacy of the percutaneous delivery of a tetramethylpyrazine-loaded microemulsion (TMP-ME) on skin pretreated with microneedles (MN).
Qiang Zu   +4 more
doaj   +1 more source

Characterisation of Drug Delivery Efficacy Using Microstructure-Assisted Application of a Range of APIs

open access: yesPharmaceutics, 2020
Polymer-based solid microstructures (MSts) have the potential to significantly increase the quantity and range of drugs that can be administered across the skin.
Raha Rahbari   +6 more
doaj   +1 more source

Oxybutynin-Nanoemulgel Formulation as a Successful Skin Permeation Strategy: In-vitro and ex-vivo Evaluation

open access: yesFrontiers in Materials, 2022
Among different topical drug delivery systems, nanoemulsions (NEs) are attractive due to enhanced skin permeation potential and minimum toxicity. Topical nanoemulgels (NEMGELs) contain both gelling agents and NEs and thus can enhance skin permeation with
Soliman Mohammadi-Samani   +6 more
doaj   +1 more source

Enhancement of Skin Delivery of Drugs Using Proposome Depends on Drug Lipophilicity

open access: yesPharmaceutics, 2021
The study aims to investigate the propylene glycol-based liposomes named ‘proposomes’ in enhancing skin permeation of drugs with different physicochemical properties. Ibuprofen, tofacitinib citrate, rhodamine B, and lidocaine were loaded into proposomes.
Himanshu Kathuria   +7 more
doaj   +1 more source

Evaluation of percutaneous permeation of repellent DEET and sunscreen oxybenzone from emulsion-based formulations in artificial membrane and human skin

open access: yesActa Pharmaceutica Sinica B, 2014
Insect repellent DEET and sunscreen ingredient oxybenzone play an essential role in minimizing vector-borne diseases and skin cancers. The purpose of this study was to investigate the effects of emulsion type, addition of thickening agent and droplet ...
Tao Wang   +3 more
doaj   +1 more source

Quantitative Structure-Permeation Relationships (QSPeRs) to Predict Skin Permeation: A Critical Evaluation [PDF]

open access: yesPharmaceutical Research, 2004
Development of reliable mathematical models to predict skin permeability remains a challenging objective. This article examines some of the existing algorithms and critically evaluates their statistical relevance.Complete statistics were recalculated for a number of published models using a stepwise multiple regression procedure.
Geinoz, S.   +3 more
openaire   +3 more sources

Systematic investigation of different formulations for drug delivery through the human nail plate "in vitro" [PDF]

open access: yes, 2010
Human nails do not have only protective and decorative role, but can also be considered as an alternative pathway for drug delivery, especially in nail diseases such as onychomycosis or psoriasis.
Vejnoviċ, Ivana
core   +1 more source

TOPICAL OLEO-HYDROGEL PREPARATIONS OF PIROXICAM WITH ENHANCED SKIN PERMEABILITY AND ANTIINFLAMMATORY ACTIVITY

open access: yesZagazig Journal of Pharmaceutical Sciences, 2000
In an attempt to improve the skin permeation and anti-inflammatory activity of piroxicam, various topical formulations including oleo-hydrogels (oleo-gels) were prepared and their in vitro diffusion, skin permeation and in vivo anti-inflammatory ...
Fergany Mohammed , Nailia Boulatova
doaj   +1 more source

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