Results 11 to 20 of about 948,428 (252)

Rapid Screening of Mupirocin Skin Permeation Modification by Micronized and Nanonized Alaptide [PDF]

ADMET and DMPK, 2014
The investigation deals with the affection of permeation of mupirocin from the Bactroban® Leciva ointment through full-thickness pig ear skin by the original Czech compound (S)-8-methyl-6,9-diazaspiro[4.5]decan-7,10-dione, known under the international ...
Josef Jampilek, Radka Opatrilova
doaj   +2 more sources

Influence of Lactobacillus Biosurfactants on Skin Permeation of Hydrocortisone

Pharmaceutics, 2021
One of the most widely used strategies to improve drug diffusion through the skin is the use of permeation enhancers. The aim of this work was to investigate the effect of two biosurfactants (BS), produced by Lactobacillus crispatus BC1 and Lactobacillus
Angela Abruzzo, Carola Parolin, Elisa Corazza, Barbara Giordani, Massimiliano Pio di Cagno, Teresa Cerchiara, Federica Bigucci, Beatrice Vitali, Barbara Luppi   +8 more
doaj   +2 more sources

Permeation of antigen protein-conjugated nanoparticles and live bacteria through microneedle-treated mouse skin

International Journal of Nanomedicine, 2011
Amit Kumar, Xinran Li, Michael A Sandoval, B Leticia Rodriguez, Brian R Sloat, Zhengrong CuiUniversity of Texas at Austin, College of Pharmacy, Pharmaceutics Division, Austin, TX, USABackground: The present study was designed to evaluate the extent to ...
Kumar A, Li X, Sandoval MA, Rodriguez BL, Sloat BR, Cui Z   +5 more
doaj   +1 more source

Animal- free skin permeation analysis using mass spectrometry imaging [PDF]

, 2021
Here we demonstrate an animal-free skin permeation analytical approach suitable for testing pharmaceuticals, cosmetics, occupational skin hazards and skin allergens.
Djuphammar, August,, Djuphammar, August, Sjölander, Linnéa,, Hagvall, Lina,, Malmberg, Per, Hagvall, Lina, Munem, Marwa, Sj\uf6lander, Linn\ue9a, Munem, Marwa,, Malmberg, Per,, Sjölander, L., Djuphammar, A., Malmberg, P., Per Malmberg, Linnea Sjölander, August Djuphammar, Marwa Munem, Lina Hagvall   +17 more
core   +1 more source

Transdermal Permeation of Drugs in Various Animal Species

Pharmaceutics, 2017
Excised human skin is utilized for in vitro permeation experiments to evaluate the safety and effect of topically-applied drugs by measuring its skin permeation and concentration. However, ethical considerations are the major problem for using human skin
Hiroaki Todo
doaj   +1 more source

Modelling the effect of mixture components on permeation through skin [PDF]

, 2010
A vehicle influences the concentration of penetrant within the membrane, affecting its diffusivity in the skin and rate of transport. Despite the huge amount of effort made for the understanding and modelling of the skin absorption of chemicals, a ...
E.G. Samaras, J.E. Riviere, Ghafourian, Taravat, Samaras, Eleftherios G., J E Riviere (16236797), E G Samaras (16236791), Riviere, Jim E., J.D. Brooks, Taravat Ghafourian (4466557), J D Brooks (16236794), Brooks, James D., T. Ghafourian   +11 more
core   +1 more source

Penetration of Chlorhexidine into Human Skin [PDF]

, 2008
This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate.
Karpanen, T. J., Conway, Barbara R, Karpanen, Tarja J., Worthington, Tony, Hilton, Anthony C., Elliott, Tom S.J., Worthington, T., Elliott, T. S. J., Lambert, Peter A., Conway, Barbara R., Lambert, P. A., Hilton, A. C.   +11 more
core   +1 more source

Mathematical Model to Predict Skin Concentration after Topical Application of Drugs

Pharmaceutics, 2013
Skin permeation experiments have been broadly done since 1970s to 1980s as an evaluation method for transdermal drug delivery systems. In topically applied drug and cosmetic formulations, skin concentration of chemical compounds is more important than ...
Hiroaki Todo, Takeshi Oshizaka, Wesam R. Kadhum, Kenji Sugibayashi   +3 more
doaj   +1 more source

IN-VITRO STUDIES ON CORTICOSTERONE PERMEATION THROUGH HAIRLESS MOUSE SKIN: ( PART I) [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2003
The use of penetration enhancer adjuvants was emerged as a growing trend intransdermal drug delivery. These adjuvants may reduce the capacity for drug binding to skinand promote the permeation of bimolecules through the skin.
Dalia. Shaker, Eman. El-leithy, Abdel Ghanem, Fahima Hashem   +3 more
doaj   +1 more source

Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas

Pharmaceutics, 2022
Infantile hemangiomas (IH) leave sequelae after involution. Topical application of timolol maleate (TM) is the mainstream treatment for superficial lesions but is limited by its low penetrable properties.
Shih-Jen Chang, Huiyuan Wang, Jialin Chen, Qianyi Chen, Lei Chang, Yongzhuo Huang, Yajing Qiu, Xiaoxi Lin   +7 more
doaj   +1 more source