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Kombucha as a Potential Active Ingredient in Cosmetics—An Ex Vivo Skin Permeation Study [PDF]
MoleculesKombucha is a non-alcoholic beverage, that is increasingly used in the cosmetic industry. The available literature reports the positive effects of kombucha on the skin, in particular its antioxidant action. However, there is a lack of information on skin
Karolina Jakubczyk +5 more
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Pharmaceutics, 2016 Generally, the blood and skin concentration profiles and steady-state skin concentration of topically applied or exposed chemicals can be calculated from the in vitro skin permeation profile. However, these calculation methods are particularly applicable
Fadli Mohd +4 more
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Photodynamic Therapy as a Novel Therapeutic Modality Applying Quinizarin-Loaded Nanocapsules and 3D Bioprinting Skin Permeation for Inflammation Treatment [PDF]
PharmaceuticalsSkin inflammation associated with chronic diseases involves a direct role of keratinocytes in its immunopathogenesis, triggering a cascade of immune responses.
Stéphanie R. do Amaral +7 more
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Novel iontophoretic drug delivery of estradiol with alendronate for osteoporosis treatment
Pakistan Journal of Pharmaceutical Sciences, 2023 Alendronate and estradiol are potential molecules for the treatment of osteoporosis but their use is limited by lower skin permeation and first-pass metabolism respectively.
Shengjie Li, Jihui Chang
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Prediction of drug permeation through microneedled skin by machine learning
Bioengineering & Translational Medicine, 2023 Stratum corneum is the outermost layer of the skin preventing external substances from entering human body. Microneedles (MNs) are sharp protrusions of a few hundred microns in length, which can penetrate the stratum corneum to facilitate drug permeation
Yunong Yuan +6 more
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Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities
Pharmaceutics, 2020 The transdermal route of drugs has received increased attention in recent years due to numerous advantages over the oral and injectable routes, such as avoidance of the hepatic metabolism, protection of drugs from the gastrointestinal tract, sustained ...
Rabin Neupane +4 more
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Human Skin Permeation Enhancement Using PLGA Nanoparticles Is Mediated by Local pH Changes
Pharmaceutics, 2021 The steady improvement and optimization of transdermal permeation is a constant and challenging pharmaceutical task. In this study the influence of poly(lactide-co-glycolide) (PLGA) nanoparticles on the dermal permeation of the anti-inflammatory drug ...
Javiana Luengo +4 more
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Pharmaceutics, 2022 The advent of skin patch formulation design and technology has enabled the commercialisation of methyl salicylate (MS) as a topical patch. However, the most fundamental aspect of skin permeation is unknown at present.
Soo Chin Yeoh +3 more
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Development and characterization of niosomal gel of fusidic acid: in-vitro and ex-vivo approaches
Designed Monomers and Polymers, 2022 Niosomes are multilamellar vesicles that efficiently deliver active substance into skin systemic circulation or skin layers. They are used in topical drug delivery system to enhance the skin permeation of active substance. So, the prime objective of this
Muhammad Khurram Waqas +9 more
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Pharmaceutics, 2023 Acyclovir (ACV) controls cutaneous herpes, genital herpes, herpes keratitis, varicella zoster, and chickenpox. From previously reported ACV formulations, we continued to explore the permeation behavior of the optimized ACV loaded optimized ethosome ...
Afzal Hussain +5 more
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