Results 1 to 10 of about 25,110 (164)
Influence of Lactobacillus Biosurfactants on Skin Permeation of Hydrocortisone [PDF]
Pharmaceutics, 2021 One of the most widely used strategies to improve drug diffusion through the skin is the use of permeation enhancers. The aim of this work was to investigate the effect of two biosurfactants (BS), produced by Lactobacillus crispatus BC1 and Lactobacillus
Angela Abruzzo +8 more
doaj +3 more sources
IAM Chromatographic Models of Skin Permeation. [PDF]
Molecules, 2022 Chromatographic retention factor log kIAM obtained from IAM HPLC chromatography with buffered aqueous mobile phases and calculated molecular descriptors (surface area—Sa; molar volume—VM; polar surface area—PSA; count of freely rotable bonds—FRB; H-bond acceptor count—HA; energy of the highest occupied molecular orbital—EHOMO; energy of the lowest ...
Sobańska AW, Brzezińska E.
europepmc +4 more sources
Kombucha as a Potential Active Ingredient in Cosmetics—An Ex Vivo Skin Permeation Study [PDF]
MoleculesKombucha is a non-alcoholic beverage, that is increasingly used in the cosmetic industry. The available literature reports the positive effects of kombucha on the skin, in particular its antioxidant action. However, there is a lack of information on skin
Karolina Jakubczyk +5 more
doaj +2 more sources
Pharmaceutics, 2016 Generally, the blood and skin concentration profiles and steady-state skin concentration of topically applied or exposed chemicals can be calculated from the in vitro skin permeation profile. However, these calculation methods are particularly applicable
Fadli Mohd +4 more
doaj +3 more sources
Pharmaceutics, 2018 The evaluation of UV-filter in vitro percutaneous absorption allows the estimation of the systemic exposure dose (SED) and the margin of safety (MoS) of sunscreen products.
Lucia Montenegro +3 more
doaj +3 more sources
Photodynamic Therapy as a Novel Therapeutic Modality Applying Quinizarin-Loaded Nanocapsules and 3D Bioprinting Skin Permeation for Inflammation Treatment [PDF]
PharmaceuticalsSkin inflammation associated with chronic diseases involves a direct role of keratinocytes in its immunopathogenesis, triggering a cascade of immune responses.
Stéphanie R. do Amaral +7 more
doaj +2 more sources
Prediction of drug permeation through microneedled skin by machine learning
Bioengineering & Translational Medicine, 2023 Stratum corneum is the outermost layer of the skin preventing external substances from entering human body. Microneedles (MNs) are sharp protrusions of a few hundred microns in length, which can penetrate the stratum corneum to facilitate drug permeation
Yunong Yuan +6 more
doaj +1 more source
HuskinDB, a database for skin permeation of xenobiotics [PDF]
Scientific Data, 2020 AbstractSkin permeation is an essential biological property of small organic compounds our body is exposed to, such as drugs in topic formulations, cosmetics, and environmental toxins. Despite the limited availability of experimental data, there is a lack of systematic analysis and structure.
Stepanov, Dmitri +2 more
openaire +2 more sources
Human Skin Permeation Enhancement Using PLGA Nanoparticles Is Mediated by Local pH Changes
Pharmaceutics, 2021 The steady improvement and optimization of transdermal permeation is a constant and challenging pharmaceutical task. In this study the influence of poly(lactide-co-glycolide) (PLGA) nanoparticles on the dermal permeation of the anti-inflammatory drug ...
Javiana Luengo +4 more
doaj +1 more source
Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities
Pharmaceutics, 2020 The transdermal route of drugs has received increased attention in recent years due to numerous advantages over the oral and injectable routes, such as avoidance of the hepatic metabolism, protection of drugs from the gastrointestinal tract, sustained ...
Rabin Neupane +4 more
doaj +1 more source