Results 21 to 30 of about 948,428 (252)
Enhanced chlorhexidine skin penetration with eucalyptus oil [PDF]
, 2010 Background Chlorhexidine digluconate (CHG) is a widely used skin antiseptic, however it poorly penetrates the skin, limiting its efficacy against microorganisms residing beneath the surface layers of skin. The aim of the current study was to improve the
Conway, Barbara R +26 more
core +2 more sources
Temperature influencing permeation pattern of alfuzosin: An investigation using DoE
Medicina, 2015 Background and objective: There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement.
Satyanarayan Pattnaik +4 more
doaj +1 more source
Novel Nanocarriers for Targeted Topical Skin Delivery of the Antioxidant Resveratrol
Pharmaceutics, 2020 Resveratrol (RSV) is a potent lipophilic antioxidant with a low aqueous solubility. Novel nanoformulations have been successfully developed and evaluated to increase the potential of resveratrol as a skin targeting antioxidant.
Christofori M. R. R. Nastiti +4 more
doaj +1 more source
Pharmaceutics, 2018 N-Palmitoyl-Glycine-Histidine (Pal-GH) is a novel low molecular weight gelator. In our previous report, ivermectin, a lipophilic drug, was effectively delivered to skin tissue after topical application with Pal-GH as a spray gel formulation, and a much ...
Sabrina Dahlizar +5 more
doaj +1 more source
Effect of Different Skin Penetration Promoters in Halobetasol Propionate Permeation and Retention in Human Skin [PDF]
, 2017 Halobetasol propionate (HB) is a potent synthetic corticosteroid used against inflammatory skin diseases, such as dermatitis, eczema, and psoriasis, among others. The aim of this study is to define how the presence of different skin penetration enhancers
Carvajal-Vidal, Paulina +7 more
core +2 more sources
A two-dimensional mathematical model of non-linear dual-sorption [PDF]
, 2005 Background: Certain drugs, for example scopolamine and timolol, show non-linear kinetic behavior during permeation process. This non-linear kinetic behavior is due to two mechanisms; the first mechanism being a simple dissolution producing mobile and ...
George K, George, K, K George
core +1 more source
In Vitro Permeation of Micronized and Nanonized Alaptide from Semisolid Formulations
The Scientific World Journal, 2013 This study is focused on in vitro permeation of the original Czech compound, a skin/mucosa tissue regeneration promoter, known under the international nonproprietary name “alaptide,” in micronized and nanonized forms.
Radka Opatrilova +4 more
doaj +1 more source
Microneedle-Assisted Percutaneous Delivery of a Tetramethylpyrazine-Loaded Microemulsion
Molecules, 2017 This study examined the efficacy of the percutaneous delivery of a tetramethylpyrazine-loaded microemulsion (TMP-ME) on skin pretreated with microneedles (MN).
Qiang Zu +4 more
doaj +1 more source
Pharmaceutics, 2020 Polymer-based solid microstructures (MSts) have the potential to significantly increase the quantity and range of drugs that can be administered across the skin.
Raha Rahbari +6 more
doaj +1 more source
Current Status of Amino Acid-Based Permeation Enhancers in Transdermal Drug Delivery
Membranes, 2021 Transdermal drug delivery (TDD) presents many advantages compared to other conventional routes of drug administration, yet its full potential has not been achieved.
Rui Pereira +4 more
doaj +1 more source