Results 51 to 60 of about 62,571 (334)
Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin [PDF]
, 2009 The history of using vesicular systems for drug delivery to and through skin started nearly three decades ago with a study utilizing phospholipid liposomes to improve skin deposition and reduce systemic effects of triamcinolone acetonide.
El Maghraby, Gamal M. +1 more
core +1 more source
Journal of Nanobiotechnology, 2008 Background Celecoxib, a selective cyclo-oxygenase-2 inhibitor has been recommended orally for the treatment of arthritis and osteoarthritis. Long term oral administration of celecoxib produces serious gastrointestinal side effects.
Ali Javed +4 more
doaj +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Formulation and in vitro/in vivo evaluation of chitosan-based film forming gel containing ketoprofen
Drug Delivery, 2017 The film forming gel, adhered to skin surfaces upon application and formed a film, has an advantage onto skin to provide protection and continuous drug release to the application site.
Dong-Won Oh +11 more
doaj +1 more source
Pharmaceutics, 2018 The evaluation of UV-filter in vitro percutaneous absorption allows the estimation of the systemic exposure dose (SED) and the margin of safety (MoS) of sunscreen products.
Lucia Montenegro +3 more
doaj +1 more source
Future Journal of Pharmaceutical Sciences, 2022 Background Transdermal drug delivery is one of the most widely used drug administration routes, which offer several advantages over other routes of drug delivery.
Bhumika Kumar +3 more
doaj +1 more source
Topical Delivery of Niacinamide to Skin Using Hybrid Nanogels Enhances Photoprotection Effect
Pharmaceutics, 2021 Niacinamide (NIA) has been widely used in halting the features of ageing by acting as an antioxidant and preventing dehydration. NIA’s physicochemical properties suggest difficulties in surpassing the barrier imposed by the stratum corneum layer to reach
Renata Basto +4 more
doaj +1 more source
Foresight into a new transdermal absorption study of cosmetics: how to evaluate transdermal absorption and skin concentration of cosmetics? [PDF]
, 2010 Skin permeation experiments have been broadly done since 1970s to 80s as an evaluation method for transdermal drug delivery systems．In cosmetic formulations，skin concentration of active ingredients is more important than their skin permeation，because ...
押坂, 勇志 +2 more
core
Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core +1 more source
Key Trends and Insights in Smart Polymeric Skin Wearable Patches
Advanced Engineering Materials, EarlyView.Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez +2 more
wiley +1 more source