Results 61 to 70 of about 62,571 (334)

Biopharmaceutical Development of a Bifonazole Multiple Emulsion for Enhanced Epidermal Delivery

Pharmaceutics, 2019
Efficient topical delivery of imidazolic antifungals faces the challenge of overcoming its limited water solubility and its required long-lasting duration of treatments.
Joaquim Suñer-Carbó, Ana Calpena-Campmany, Lyda Halbaut-Bellowa, Beatriz Clares-Naveros, María José Rodriguez-Lagunas, Elena Barbolini, Joanna Zamarbide-Losada, Antonio Boix-Montañés   +7 more
doaj   +1 more source

Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles. [PDF]

, 2018
Cutaneous leishmaniasis (CL) is caused by several species of the protozoan parasite Leishmania, affecting an estimated 10 million people worldwide. Previously reported strategies for the development of topical CL treatments have focused primarily on drug
Croft, Simon L, Gaukel, Eric, Hauser, Deirdre, Jacobs, Robert T, Merchant, Tejal, Park, Seong Hee, Plattner, Jacob J, Randolph, Ryan, Schock, Sara, Van Bocxlaer, Katrien, Wring, Stephen A, Yardley, Vanessa   +11 more
core   +1 more source

In‐Situ Growth of 2D MOFs as a Molecular Sieving Layer on SnS2 Nanoflakes for Realizing Ultraselective H2S Detection

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
The ultraselective H2S detection of the ZIF‐L/SnS2 heterostructure is demonstrated. The introduction of 2‐dimensional (2D) breathable ZIF‐L results in a substantial increase in H2S selectivity attributable to the molecular sieving effect, which impedes the permeation of gases with large kinetic diameters and high polarity.
Soo Min Lee, Yeong Jae Kim, Seon Ju Park, Woo Seok Cheon, Jaehyun Kim, Gi Baek Nam, Youngeun Kim, Ho Won Jang   +7 more
wiley   +1 more source

Stratum Corneum‐Inspired Zwitterionic Hydrogels with Intrinsic Water Retention and Anti‐Freezing Properties for Intelligent Flexible Sensors

Advanced Functional Materials, EarlyView.
A novel stratum corneum‐inspired zwitterionic hydrogel is developed for intelligent, flexible sensors, featuring intrinsic water retention and anti‐freezing properties. The quasi‐gel, composed of hygroscopic polymers and bound water, maintains its softness across a wide range of humidity.
Meng Wu, Chenyu Qiao, Peng‐Fei Sui, Jing‐Li Luo, Zuoli Li, Yi Cao, Renjun Pei, Xuwen Peng, Hongbo Zeng   +8 more
wiley   +1 more source

A Mathematical Approach Using Strat-M^® to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions

Pharmaceutics, 2022
Estimation of the percutaneous absorption is essential for the safety assessment of cosmetic and dermopharmaceutical products. Currently, an artificial membrane, Strat-M®, has been focused on as the tool which could obtain the permeation parameters close
Ryoki Kunita, Takafumi Nishijima, Hiroaki Todo, Kenji Sugibayashi, Hitoshi Sakaguchi   +4 more
doaj   +1 more source

The Importance of Hydration in Wound Healing: Reinvigorating the clinical perspective [PDF]

, 2016
Balancing skin hydration levels is important as any disruption in skin integrity will result in disturbance of the dermal water balance. The discovery that a moist wound healing environment actively supports the healing response when compared to a dry ...
Atiyeh B.S., Atiyeh B.S., Eaglstein W.H., Faria D., Gabriel A., Gabriel A., Gray D., Hebra F., Leung B.K., Park A.C., Rubio P.A., Scheuplein R., Verdier-Sévrain S., Xu W., Zelen C.M.   +14 more
core   +1 more source

Integration of Perovskite/Low‐Dimensional Material Heterostructures for Optoelectronics and Artificial Visual Systems

Advanced Functional Materials, EarlyView.
Heterojunctions combining halide perovskites with low‐dimensional materials enhance optoelectronic devices by enabling precise charge control and improving efficiency, stability, and speed. These synergies advance flexible electronics, wearable sensors, and neuromorphic computing, mimicking biological vision for real‐time image analysis and intelligent
Yu‐Jin Du, Junjie Yang, Ziyu Lv, Yongbiao Zhai, Zezhuang Yi, Yuhui Xie, Ming‐Lin Zheng, Xiangyu Ma, Guodong Gong, Yan Wang, Ye Zhou, Su‐Ting Han   +11 more
wiley   +1 more source

Usefulness of Artificial Membrane, Strat-M^®, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions

Pharmaceutics, 2020
The ban on the use of animals in testing cosmetic products has led to the development of animal-free in vitro methods. Strat-M® is an artificial membrane engineered to mimic human skin and is recommended as a replacement for skin.
Florencio Jr Arce, Narumi Asano, Gerard Lee See, Shoko Itakura, Hiroaki Todo, Kenji Sugibayashi   +5 more
doaj   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Calcipotriol delivery into the skin as emulgel for effective permeation

Saudi Pharmaceutical Journal, 2014
The objective of this work is to formulate and evaluate an emulgel containing calcipotriol for treatment of psoriasis. Emulgels have emerged as a promising drug delivery system for the delivery of hydrophobic drugs. Isopropyl alcohol and polyethylene glycol have been employed as permeation enhancers.
Sharath Chandra Reddy, Devegowda Vishakante Gowda, M. Navya, P.V. Maheshwari, Hosakote G. Shivakumar, V. Naga Sravan Kumar Varma   +5 more
openaire   +3 more sources