Results 61 to 70 of about 1,692,764 (393)

Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts

open access: yesScientific Reports, 2019
Ascorbic acid (AA) is widely used in cosmetic formulations due to its antioxidant property and ability to increase collagen synthesis. Here, we encapsulated AA in vesicles with different lipid compositions.
Lorena Maione-Silva   +7 more
semanticscholar   +1 more source

Human skin in vitro permeation of bentazon and isoproturon formulations with or without protective clothing suit [PDF]

open access: yes, 2013
Skin exposures to chemicals may lead, through percutaneous permeation, to a significant increase in systemic circulation. Skin is the primary route of entry during some occupational activities, especially in agriculture. To reduce skin exposures, the use
Baldi, Isabelle   +7 more
core   +1 more source

Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations

open access: yesAAPS PharmSciTech
Percutaneous delivery is explored as alternative pathway for addressing the drawbacks associated with the oral administration of otherwise efficacious drugs.
J. Musakhanian   +2 more
semanticscholar   +1 more source

Skin permeation mechanism and bioavailability enhancement of celecoxib from transdermally applied nanoemulsion

open access: yesJournal of Nanobiotechnology, 2008
Background Celecoxib, a selective cyclo-oxygenase-2 inhibitor has been recommended orally for the treatment of arthritis and osteoarthritis. Long term oral administration of celecoxib produces serious gastrointestinal side effects.
Ali Javed   +4 more
doaj   +1 more source

Formulation and in vitro/in vivo evaluation of chitosan-based film forming gel containing ketoprofen

open access: yesDrug Delivery, 2017
The film forming gel, adhered to skin surfaces upon application and formed a film, has an advantage onto skin to provide protection and continuous drug release to the application site.
Dong-Won Oh   +11 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Cutaneous Permeation of a Percutaneously Applied Glucocorticoid Using Plant-Based Anionic Phospholipids in Hydrogenated Vegetable Oil: A Preliminary Study

open access: yesMedicina, 2022
Purpose: It is important that, when corticosteroids are used therapeutically, concentrations be reduced as much as possible to mitigate potential adverse events and side effects.
Jack V. Greiner   +5 more
doaj   +1 more source

Foresight into a new transdermal absorption study of cosmetics: how to evaluate transdermal absorption and skin concentration of cosmetics? [PDF]

open access: yes, 2010
Skin permeation experiments have been broadly done since 1970s to 80s as an evaluation method for transdermal drug delivery systems.In cosmetic formulations,skin concentration of active ingredients is more important than their skin permeation,because ...
押坂, 勇志   +2 more
core  

A Novel Polymer Insect Repellent Conjugate for Extended Release and Decreased Skin Permeation of Para-Menthane-3,8-Diol

open access: yesPharmaceutics, 2021
Background: We developed a novel polymer insect repellent conjugate for extended release and decreased skin permeation of the volatile insect repellent p-menthane-3,8-diol (PMD).
Sayyed I. Shah   +2 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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