Results 61 to 70 of about 818,958 (236)

TGFβ Signaling in Photoaging and UV-Induced Skin Cancer [PDF]

, 2021
UVR is a major etiology for premature skin aging that leads to photoaging and UV-induced skin cancers. In the skin, TGFβ signaling is a growth inhibitor for keratinocytes and a profibrotic factor in the dermis.
Ke, Yao, Wang, Xiao-Jing
core   +1 more source

The Physician Global Assessment as a Proxy for Photoaging: Validation in an Observational Real‐World Cohort Using SCINEXA as the Reference Standard

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Photoaging is a chronic skin condition caused by cumulative ultraviolet exposure superimposed on intrinsic aging. Although the SCore of INtrinsic and EXtrinsic skin Aging (SCINEXA) is a validated multidimensional instrument for assessing photoaging, the Physician Global Assessment (PGA) is a simpler clinician‐reported measure whose ...
Ewout Baerveldt, Eric van Sprang, Henk‐Jan Ramaker, Robert T. Aeneae Venema, Thomas Rustemeyer, Jorrit Terra, Perry J. J. van Genderen   +6 more
wiley   +1 more source

Efficacy and Safety of Small‐Spot 755 nm Picosecond Laser‐Induced Optical Breakdown for Novel Photomechanical Skin Ablation in Asian Patients

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Conventional ablative and photothermal lasers are commonly used to treat superficial pigmentary lesions but often induce thermal injury and post‐inflammatory hyperpigmentation (PIH), particularly in Asian skin. Picosecond 755‐nm alexandrite lasers with diffractive lens arrays (DLA) create laser‐induced optical breakdown (LIOB ...
Nai‐Wen Chai, Wan‐Chun Liao, Chang‐Cheng Chang, Po‐Hsuan Wei, Yung‑Hsueh Huang, Ying‐Chuan Hsu, Yen‑Jen Wang, Yu‐Tsung Chen   +7 more
wiley   +1 more source

Effects of visible light on mechanisms of skin photoaging

, 2021
Human skin is not only affected by ultraviolet radiation but also by visible light wavelengths emitted by sunlight, electronic devices, and light emitting diodes. Similar to the ultraviolet radiation, visible light has been implicated in photoaging.
Torres, Angeli E, Pourang, Aunna, Hamzavi, Iltefat H, Tisack, Aaron, Lim, Henry W, Ezekwe, Nneamaka, Kohli, Indermeet   +6 more
core   +1 more source

Peptide CyRL-QN15 alleviates UVB-induced skin aging by promoting the repair of barrier

Ecotoxicology and Environmental Safety
Skin photoaging, a process with substantial physical and psychological impacts, is also a recognized risk factor for skin cancer. Despite advancements in dermatological research, effective prevention and reversal of photoaging remain challenging.
Zijian Kang, Saige Yin, Xiaoya Han, Xin Liu, Ying Peng, Qiuye Jia, Zhe Fu, Yuansheng Li, Yutong Wu, Zhaoxun Xiao, Zhiruo Li, Ying Wang, Mingying Luo, Xinwang Yang   +13 more
doaj   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Synergistic delivery of hADSC-Exos and antioxidants has inhibitory effects on UVB-induced skin photoaging

Heliyon
Ultraviolet B (UVB) light exposure accelerates skin photoaging. Human adipose-derived stem cell exosomes (hADSC-Exos) and some antioxidants may have anti-photoaging effects.
Yu Fu, Jun-ling Xie, Wan-ting Zhang, Xing-liao Zhang, Xin-Min Zhang, Meng-meng Xu, Yao-ting Han, Rong-qi Liu, Guang-ming Xie, Jing Zhang, Jun Zhang   +10 more
doaj   +1 more source

Adipose-Derived Mesenchymal Stem Cells (AD-MSCs) against Ultraviolet (UV) Radiation Effects and the Skin Photoaging

Biomedicines, 2021
The skin is a natural barrier against the ultraviolet (UV) radiation of sunlight. The long-term and/or repetitive exposure to the sunlight and related UV radiation may change the skin structure, decreasing collagen production, promoting premature skin ...
Pietro Gentile, Simone Garcovich
doaj   +1 more source

A Novel Antioxidant Peptide Cath‐Np Derived from Nanorana parkeri Attenuates UVB‐Induced Skin Photodamage in Mice

Integrative Zoology, EarlyView.
Schematic representation of Cath‐Np as an antioxidant suppressing acute skin damage caused by ultraviolet B (UVB) radiation in mice. Cath‐Np inhibits the activation of p53 and mitogen‐activated protein kinase pathways while it activates the Nrf2 pathway by its strong antioxidant effects, and accordingly suppresses the expression of inflammatory factors
Hang Liao, Xiaoxiao Shen, Jinwei Chai, Kai wang, Jiena Wu, Jianxi Yang, Ming Chen, Guoxiang Mo, Xueqing Xu   +8 more
wiley   +1 more source

Sunscreens - Which and what for? [PDF]

, 2005
It is well established that sun exposure is the main cause for the development of skin cancer. Chronic continuous UV radiation is believed to induce malignant melanoma, whereas intermittent high-dose UV exposure contributes to the occurrence of actinic ...
Korting, Hans Christian, Maier, T.
core   +1 more source