Results 81 to 90 of about 14,260 (223)

Health Care Evolves From Reactive to Proactive. [PDF]

, 2019
Decoding health and disease pathways drives healthcare evolution. Historically, therapeutic paradigms have relied on interventions that mitigate symptoms of established diseases.
Terzic, Andre, Waldman, Scott A.
core   +2 more sources

A Comprehensive Review of Traditional and Machine Learning‐Assisted Diffuse Optical Spectroscopy and Imaging Techniques for Dermatological Applications

Advanced Photonics Research, Volume 7, Issue 5, May 2026.
This review critically examines clinical studies on both conventional and machine learning (ML)‐integrated diffuse optical spectroscopy and imaging methods for dermatological applications, with a primary focus on the past decade and inclusion of earlier foundational work where appropriate.
Iftak Hussain, Li Xiuting, Randall Ang Jie, Keertana Vinod Ram, Mark Teo Ju Teng, Valerie Xinhui Teo, Malini Olivo, U. S. Dinish   +7 more
wiley   +1 more source

Human collagen III mRNA therapy for effective skin rejuvenation

Journal of Translational Medicine
Background Skin photoaging leads to the deterioration of dermal collagen and overall skin integrity, resulting in visible signs of aging, particularly around the eye.
Jiamin Zhang, Shuqi Chen, Jiaqi Yang, Lianhao Song, Linfeng Chen, Wei Feng, Rong Ju, Zhi Xie   +7 more
doaj   +1 more source

Age and sun exposure-related widespread genomic blocks of hypomethylation in nonmalignant skin [PDF]

, 2015
BACKGROUND: Aging and sun exposure are the leading causes of skin cancer. It has been shown that epigenetic changes, such as DNA methylation, are well established mechanisms for cancer, and also have emerging roles in aging and common disease.
Amy R Vandiver, Andrew P Feinberg, Anna L Chien, Arni Runarsson, Kasper D Hansen, Luis A Garza, Rafael A Irizarry, Sewon Kang, Sherry G Leung, Timothy S Wang, Xin Li   +10 more
core   +1 more source

Photophysics of Biological and Biomimetic Sunscreen Molecules

ChemPhotoChem, Volume 10, Issue 5, May 2026.
Recent photochemical and photophysical research into natural and nature‐inspired UV filter molecules is reviewed, with a focus on the application of these systems in next‐generation sunscreens. The results of time‐resolved UV spectroscopy experiments and theoretical studies are discussed.
Michael Hymas, Vasilios G. Stavros
wiley   +1 more source

Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo. [PDF]

, 2003
peer reviewedaudience: researcherVitamin C is known for its antioxidant potential and activity in the collagen biosynthetic pathway. Photoprotective properties of topically applied vitamin C have also been demonstrated, placing this molecule as a ...
Abbey, Agache, Alain Richard, André Rougier, Betty Nusgens, Beyer, Bisset, Black, Braverman, Charles Lapière, Chung, Colven, Cook, Corcuff, Creidi, Daniel Schmitt, Darr, Darr, Dumas, Fitzpatrick, Gilchrest, Grove, Grove, Hassan Zahouani, Makki, Makki, Marek Haftek, Mays, Mignot, Murad, Murad, Murad, Murad, Murray, Nusgens, Padh, Philippe G. Humbert, Phillips, Pierre Creidi, Pinnel, Pinnell, Ranodive, Traikovich, Zahouani   +43 more
core   +1 more source

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil, Feng Zhang, Jingchuan Zheng, Muhammad Kamil, Yuwei Guo, Cunchao Zhao, Yang Tian   +6 more
wiley   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

Food Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz, Alejandra Romero‐Montero, Hector Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, Fabio Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, Daniela Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez   +13 more
wiley   +1 more source

Unveiling the dual-edged roles of melanocytes: Key insights into skin photoaging and therapeutic avenues

Pharmacological Research
The skin, the body's largest organ, serves as the primary barrier against external damage. Skin aging can act as a visible proxy and a triggering factor for systemic aging.
Xiaorong Jia, Li He
doaj   +1 more source

Alterations in extracellular matrix composition during aging and photoaging of the skin

Matrix Biology Plus, 2020
Human skin is composed of the cell-rich epidermis, the extracellular matrix (ECM) rich dermis, and the hypodermis. Within the dermis, a dense network of ECM proteins provides structural support to the skin and regulates a wide variety of signaling ...
Maxwell C. McCabe, Ryan C. Hill, Kenneth Calderone, Yilei Cui, Yan Yan, Taihao Quan, Gary J. Fisher, Kirk C. Hansen   +7 more
doaj   +1 more source