Results 71 to 80 of about 818,958 (236)

Amphibian‐Derived Peptide OA‐AL14 Alleviates UVB‐Induced Skin Photoaging via Autophagy Activation Mediated by the AMPK/mTOR Pathway

Integrative Zoology, EarlyView.
The schematic diagram illustrates that the amphibian‐derived peptide OA‐AL14 protects against UVB‐induced skin photoaging through a dual mechanism: activating the Nrf2 pathway to counteract oxidative stress and modulating the AMPK/mTOR axis to induce protective autophagy. ABSTRACT Skin photoaging, primarily driven by ultraviolet B (UVB) radiation, is a
Ying Peng, Yutong Wu, Zhe Fu, Zijian Kang, Qiuye Jia, Wenbi Zhao, Ziyi Wang, Yuexi Liu, Ruijie Zhang, Yuansheng Li, Zeqiong Ru, Wenrou Su, Naixin Liu, Yilin Li, Saige Yin, Ying Wang, Xinwang Yang   +16 more
wiley   +1 more source

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

International Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques, Filipa Teixeira, Mónica Vieira, M. Helena Amaral, Paulo C. Costa, Stefano Dall'Acqua, Francisca Rodrigues   +6 more
wiley   +1 more source

Skin aging and photoaging: An overview

Journal of the American Academy of Dermatology, 1989
As the population ages, common skin disorders of the elderly demand greater attention. Moreover, the many clinical, histologic, and physiologic changes that characterize old skin are increasingly implicated in its vulnerability to environmental injury and certain diseases.
openaire   +2 more sources

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Trans‐resveratrol alleviates inflammation and improves skin barrier function via aryl hydrocarbon receptor pathway in human reconstructed epidermis

International Journal of Cosmetic Science, EarlyView.
In a cytokine‐challenged human epidermal model, trans‐resveratrol reduces inflammation (IL‐1α) and oxidative stress markers (CYP1A1, CYP1B1), while modulating the expression of barrier‐related genes (LOR, OCLN) and differentiation‐associated CASP14. This supports its role as a multifunctional active for sensitive and compromised skin.
Irini M. Dijkhoff, Sandeep Keshavan, Regina G. Daré, Alke Petri‐Fink, Marc Eeman, Agnès Tessier, Barbara Rothen‐Rutishauser   +6 more
wiley   +1 more source

Enzyme-Treated Caviar Prevents UVB Irradiation-Induced Skin Photoaging

, 2022
For this research article, we investigated the protective effects of enzyme-treated caviar powder extract (CV) in ultraviolet B (UVB)-irradiated hairless mice and keratinocytes by confirming moisturizing-related factors and elasticity-related factors ...
Han, Jehee, Sangshin Han, Minhee Lee, Park, Jeongjin, Hyun Mook Jung, Na, Gwi Hwan, Ok-Kyung Kim, Jung, Hyun Mook, Lee, Minhee, Kim, Dakyung, Gwi Hwan Na, Jeongjin Park, Dakyung Kim, Woojin Jun, Han, Sang Hun, Han, Sangshin, Jun, Woojin, Kim, Ok-Kyung, Koo, Yean Kyoung, Jehee Han, Yean Kyoung Koo, Sang Hun Han   +21 more
core   +1 more source

Cosmetic Dermatology in Pregnancy and Lactation: A Risk–Benefit Framework for Clinical Practice

International Journal of Dermatology, EarlyView.
Summary of the safety profile of common cosmetic dermatology interventions during pregnancy and lactation. ABSTRACT Cosmetic dermatologic products and procedures are increasingly utilized by women of reproductive age, including those who are pregnant or lactating.
Timea Kovacs, Umer Nadir, Michael Goldenberg, Thomas E. Rohrer, Deirdre Hooper, George M. Jeha, Stanislav N. Tolkachjov   +6 more
wiley   +1 more source

3D Monte Carlo radiation transfer modelling of photodynamic therapy [PDF]

, 2015
We acknowledge the support of the UK Engineering and Physics Sciences Research Council (EPSRC) for funding through a studentship for C L Campbell as well as the Alfred Stewart Trust.The effects of ageing and skin type on Photodynamic Therapy (PDT) for ...
Wood, Kenneth, Valentine, Ronan M., Christison, C., C. Louise Campbell, Campbell, C. Louise, Kenneth Wood, Brown, C Tom A, Moseley, H., Moseley, Harry, C. Tom A. Brown, Campbell, Catherine Louise, Harry Moseley, Wood, Kenny, Brown, C. Tom A, Craig Christison, Ronan M. Valentine, Christison, Craig, Valentine, Ronan Martin   +17 more
core   +1 more source

Skin photoaging in farmers professionally exposed to ultraviolet radiations

, 2013
Background: Most personal exposures to UV radiations occur from outdoor activities and several studies detected a significant association between skin cancer and outdoor occupation.
Romeo R., Paolucci V., Di Simplicio F., Sartorelli P., Barabesi L., Puzzo V.   +5 more
core   +1 more source