Results 1 to 10 of about 129,837 (266)

Hydrogel-Based Skin Regeneration. [PDF]

Int J Mol Sci
The skin is subject to damage from the surrounding environment. The repair of skin wounds can be very challenging due to several factors such as severe injuries, concomitant infections, or comorbidities such as diabetes. Different drugs and wound dressings have been used to treat skin wounds.
Arabpour Z, Abedi F, Salehi M, Baharnoori SM, Soleimani M, Djalilian AR.   +5 more
europepmc   +3 more sources

Advances and applications of biomimetic biomaterials for endogenous skin regeneration [PDF]

Bioactive Materials
Endogenous regeneration is becoming an increasingly important strategy for wound healing as it facilitates skin's own regenerative potential for self-healing, thereby avoiding the risks of immune rejection and exogenous infection.
Mengyang Wang, Yiyue Hong, Xiaobing Fu, Xiaoyan Sun   +3 more
doaj   +2 more sources

Therapeutic potential of exosomes from adipose-derived stem cells in chronic wound healing

Frontiers in Surgery, 2022
Chronic wound healing remains a challenging medical problem affecting society, which urgently requires anatomical and functional solutions. Adipose-derived stem cells (ADSCs), mesenchymal stem cells with self-renewal and multiple differentiation ability,
Chengmin Long, Chengmin Long, Jingru Wang, Jingru Wang, Wenjun Gan, Wenjun Gan, Xinchi Qin, Xinchi Qin, Ronghua Yang, Ronghua Yang, Xiaodong Chen, Xiaodong Chen   +11 more
doaj   +1 more source

The Landscape of the Tumor Microenvironment in Skin Cutaneous Melanoma Reveals a Prognostic and Immunotherapeutically Relevant Gene Signature

Frontiers in Cell and Developmental Biology, 2021
The tumorigenesis of skin cutaneous melanoma (SKCM) remains unclear. The tumor microenvironment (TME) is well known to play a vital role in the onset and progression of SKCM. However, the dynamic mechanisms of immune regulation are insufficient.
Sitong Zhou, Yidan Sun, Tianqi Chen, Jingru Wang, Jia He, Jin Lyu, Yanna Shen, Xiaodong Chen, Ronghua Yang   +8 more
doaj   +1 more source

Nanomaterials in Skin Regeneration and Rejuvenation [PDF]

International Journal of Molecular Sciences, 2021
Skin is the external part of the human body; thus, it is exposed to outer stimuli leading to injuries and damage, due to being the tissue mostly affected by wounds and aging that compromise its protective function. The recent extension of the average lifespan raises the interest in products capable of counteracting skin related health conditions ...
Emanuela Bellu, Serenella Medici, Donatella Coradduzza, Sara Cruciani, Evzen Amler, Margherita Maioli   +5 more
openaire   +3 more sources

Small molecules facilitate single factor-mediated sweat gland cell reprogramming

Military Medical Research, 2022
Background Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogramming strategy to convert fibroblasts
Shuai-Fei Ji, Lai-Xian Zhou, Zhi-Feng Sun, Jiang-Bing Xiang, Shao-Yuan Cui, Yan Li, Hua-Ting Chen, Yi-Qiong Liu, Huan-Huan Gao, Xiao-Bing Fu, Xiao-Yan Sun   +10 more
doaj   +1 more source

Biomask for Skin Regeneration [PDF]

Regenerative Medicine, 2014
Critical challenges in facial skin wound healing The use of helmets and body armor in mod­ ern warfare greatly reduces the mortality and severity of injury for soldiers. However, facial injuries resulting from improvised explosive devices (IEDs), gun shots and burns are still common.
XingGuo, Cheng, James J, Yoo, Robert G, Hale   +2 more
openaire   +2 more sources

Effects of exosomes derived from placental mesenchymal stem cells on high glucose-induced senescence in human dermal fibroblasts

Di-san junyi daxue xuebao, 2020
Objective To explore the optimal conditions for inducing senescence in human dermal fibroblasts (HDFs) cultured in high glucose and observe the effect of exosomes derived from human placental mesenchymal stem cells (PMSCs) on the proliferation, migration
BIAN Xiaowei, BIAN Xiaowei, ZHANG Cuiping, LI Bingmin, MA Kui, YANG Jie, FU Xiaobing   +6 more
doaj   +1 more source

Acidic and hypoxic tumor microenvironment regulation by CaO2-loaded polydopamine nanoparticles

Journal of Nanobiotechnology, 2022
Hypoxia and high accumulation of lactic acid in the tumor microenvironment provide fertile soil for tumor development, maintenance and metastasis. Herein, we developed a calcium peroxide (CaO2)-loaded nanostructure that can play a role of “one stone kill
Shuangrong Ruan, Weimin Yin, Jiao Chang, Yan Yang, Jiuyuan Sun, Xiaoyi Ma, Ying Liu, Jie Zang, Yiqiong Liu, Yongyong Li, Tianbin Ren, Haiqing Dong   +11 more
doaj   +1 more source

Identification of Novel Biomarkers With Diagnostic Value and Immune Infiltration in Burn Injury

Frontiers in Genetics, 2022
Burn injury is an intractable problem in the field of surgery where screening relevant target genes and exploring pathological mechanisms through bioinformatic methods has become a necessity.
Sitong Zhou, Kangchun Wang, Jingru Wang, Jia He, Wenlian Zheng, Chengmin Long, Xiaodong Chen, Ronghua Yang   +7 more
doaj   +1 more source