Results 11 to 20 of about 129,837 (266)

Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases

Signal Transduction and Targeted Therapy, 2023
The ageing process is a systemic decline from cellular dysfunction to organ degeneration, with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells or organisms more youthful characteristics through various techniques ...
Shuaifei Ji, Mingchen Xiong, Huating Chen, Yiqiong Liu, Laixian Zhou, Yiyue Hong, Mengyang Wang, Chunming Wang, Xiaobing Fu, Xiaoyan Sun   +9 more
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Skin Regeneration, Repair, and Reconstruction [PDF]

BioMed Research International, 2015
Skin has important functions in several life-preserving processes such as hydration, protection against chemicals and pathogens, and heat regulation. Severe damage to the skin may therefore be life-threatening. Skin regeneration and wound healing require an orchestrated integration of complex biological and molecular events, which include ...
Kamolz, Lars-Peter, Griffith, May, Finnerty, Celeste, Kasper, Cornelia   +3 more
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Functional hair follicle regeneration: an updated review

Signal Transduction and Targeted Therapy, 2021
The hair follicle (HF) is a highly conserved sensory organ associated with the immune response against pathogens, thermoregulation, sebum production, angiogenesis, neurogenesis and wound healing. Although recent advances in lineage-tracing techniques and
Shuaifei Ji, Ziying Zhu, Xiaoyan Sun, Xiaobing Fu   +3 more
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Pleiotropic Roles of CXCR4 in Wound Repair and Regeneration

Frontiers in Immunology, 2021
Wound healing is a multi-step process that includes multiple cellular events such as cell proliferation, cell adhesion, and chemotactic response as well as cell apoptosis.
Huating Chen, Huating Chen, Gongchi Li, Yiqiong Liu, Shuaifei Ji, Yan Li, Yan Li, Jiangbing Xiang, Jiangbing Xiang, Laixian Zhou, Huanhuan Gao, Wenwen Zhang, Xiaoyan Sun, Xiaobing Fu, Binghui Li   +14 more
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A MUSE for Skin Regeneration [PDF]

Journal of Investigative Dermatology, 2017
With a rise in the prevalence of chronic wounds and other soft tissue defects, there is an urgent need to regenerate skin. Multilineage-differentiating stress-enduring cells were identified as distinct pluripotent stem cells in mesenchymal cell populations in humans.
Michael S, Hu, Michael T, Longaker
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Redirecting differentiation of mammary progenitor cells by 3D bioprinted sweat gland microenvironment

Burns & Trauma, 2019
Background Mammary progenitor cells (MPCs) maintain their reproductive potency through life, and their specific microenvironments exert a deterministic control over these cells.
Rui Wang, Yihui Wang, Bin Yao, Tian Hu, Zhao Li, Yufan Liu, Xiaoli Cui, Liuhanghang Cheng, Wei Song, Sha Huang, Xiaobing Fu   +10 more
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Research status and hot topics of the effects of skin innervation on wound healing from 1959 to 2022: A bibliometric analysis

Frontiers in Surgery, 2022
BackgroundSkin innervation plays an important role in wound healing by either direct contact with or indirect secretions that impact skin cells. Many studies in this field have been published; however, there is a lack of bibliometric analyses focusing on
Ru Song, Ru Song, Zhenjie Wu, Zhenjie Wu, Jiaxu Ma, Jiaxu Ma, Siyuan Yin, Siyuan Yin, Chunyan Liu, Chunyan Liu, Rui Sun, Rui Sun, Guoqi Cao, Guoqi Cao, Yongpan Lu, Yongpan Lu, Aoyu Chen, Aoyu Chen, Guang Zhang, Guang Zhang, Jian Liu, Jian Liu, Yibing Wang, Yibing Wang, Yibing Wang   +24 more
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Wound Healing and Skin Regeneration [PDF]

Cold Spring Harbor Perspectives in Medicine, 2015
The skin is a complex organ consisting of the epidermis, dermis, and skin appendages, including the hair follicle and sebaceous gland. Wound healing in adult mammals results in scar formation without any skin appendages. Studies have reported remarkable examples of scarless healing in fetal skin and appendage regeneration in adult skin following the ...
Makoto, Takeo, Wendy, Lee, Mayumi, Ito
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Irf6 directs glandular lineage differentiation of epidermal progenitors and promotes limited sweat gland regeneration in a mouse burn model

Stem Cell Research & Therapy, 2018
Background Damaged or malfunctioning sweat glands (SGs) after a burn injury would cause significant hyperthermia and even death, and there is an unmet need for effective treatment.
Bin Yao, Wei Song, Zhao Li, Tian Hu, Rui Wang, Yihui Wang, Sha Huang, Xiaobing Fu   +7 more
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Sweat Gland Organoids Originating from Reprogrammed Epidermal Keratinocytes Functionally Recapitulated Damaged Skin

Advanced Science, 2021
Restoration of sweat glands (SwGs) represents a great issue in patients with extensive skin defects. Recent methods combining organoid technology with cell fate reprogramming hold promise for developing new regenerative methods for SwG regeneration. Here,
Xiaoyan Sun, Jiangbing Xiang, Runkai Chen, Zhijun Geng, Lintao Wang, Yiqiong Liu, Shuaifei Ji, Huating Chen, Yan Li, Cuiping Zhang, Peng Liu, Tao Yue, Lei Dong, Xiaobing Fu   +13 more
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