Results 21 to 30 of about 129,837 (266)

Therapeutic angiogenesis using stem cell-derived extracellular vesicles: an emerging approach for treatment of ischemic diseases

Stem Cell Research & Therapy, 2019
Ischemic diseases, which are caused by a reduction of blood supply that results in reduced oxygen transfer and nutrient uptake, are becoming the leading cause of disabilities and deaths. Therapeutic angiogenesis is key for the treatment of these diseases.
Xiaowei Bian, Kui Ma, Cuiping Zhang, Xiaobing Fu   +3 more
doaj   +1 more source

3D skin bioprinting: future potential for skin regeneration

Advances in Dermatology and Allergology, 2022
Skin provides protection against external agents and plays an essential role in maintaining the body homeostasis. Bioprinting as a novel strategy involves computer-controlled deposition of cells and scaffolds into a three-dimensional (3D) construction of skin.
Pasierb, Anna, Jezierska, Marta, Karpuk, Aleksandra, Czuwara, Joanna, Rudnicka, Lidia   +4 more
openaire   +2 more sources

Macrophage Related Chronic Inflammation in Non-Healing Wounds

Frontiers in Immunology, 2021
Persistent hyper-inflammation is a distinguishing pathophysiological characteristic of chronic wounds, and macrophage malfunction is considered as a major contributor thereof. In this review, we describe the origin and heterogeneity of macrophages during
Meirong Li, Meirong Li, Meirong Li, Meirong Li, Qian Hou, Qian Hou, Qian Hou, Lingzhi Zhong, Lingzhi Zhong, Lingzhi Zhong, Yali Zhao, Xiaobing Fu, Xiaobing Fu, Xiaobing Fu   +13 more
doaj   +1 more source

Gongying-Jiedu-Xiji recipe promotes the healing of venous ulcers by inhibiting ferroptosis via the CoQ-FSP1 axis

Frontiers in Pharmacology, 2023
Objective: Gongying-Jiedu-Xiji recipe (DDL, batch number Z01080175) reduces body temperature, detoxifies, activates the blood circulation, reduces swelling, and dispels decay and pus.
Yongpan Lu, Yongpan Lu, Dejie Zhao, Ming Liu, Guoqi Cao, Guoqi Cao, Chunyan Liu, Chunyan Liu, Siyuan Yin, Siyuan Yin, Ru Song, Ru Song, Jiaxu Ma, Jiaxu Ma, Rui Sun, Rui Sun, Zhenjie Wu, Zhenjie Wu, Jian Liu, Jian Liu, Yibing Wang, Yibing Wang   +21 more
doaj   +1 more source

Skin regeneration of amphibians: A novel model for skin regeneration as adults [PDF]

Development, Growth & Differentiation, 2018
Adult mammals do not regenerate the dermis of the skin but form a scar after a deep skin injury. Since a scar causes serious medical problems, skin regeneration, instead of formation of a scar, has been strongly desired from a clinical point of view. Recent studies have suggested multiple origins of myofibroblasts, which are scar‐forming cells in skin ...
Hitoshi Yokoyama, Nanako Kudo, Momoko Todate, Yuri Shimada, Makoto Suzuki, Koji Tamura   +5 more
openaire   +2 more sources

Biophysical and Biochemical Cues of Biomaterials Guide Mesenchymal Stem Cell Behaviors

Frontiers in Cell and Developmental Biology, 2021
Mesenchymal stem cells (MSCs) have been widely used in the fields of tissue engineering and regenerative medicine due to their self-renewal capabilities and multipotential differentiation assurance.
Jianjun Li, Jianjun Li, Jianjun Li, Yufan Liu, Yufan Liu, Yijie Zhang, Yijie Zhang, Bin Yao, Bin Yao, Bin Yao, Enhejirigala, Enhejirigala, Enhejirigala, Enhejirigala, Zhao Li, Wei Song, Wei Song, Yuzhen Wang, Yuzhen Wang, Yuzhen Wang, Xianlan Duan, Xianlan Duan, Xianlan Duan, Xingyu Yuan, Xingyu Yuan, Xingyu Yuan, Xiaobing Fu, Xiaobing Fu, Xiaobing Fu, Sha Huang   +29 more
doaj   +1 more source

Modeling human hypertrophic scars with 3D preformed cellular aggregates bioprinting

Bioactive Materials, 2022
The therapeutic interventions of human hypertrophic scars (HHS) remain puzzle largely due to the lack of accepted models. Current HHS models are limited by their inability to mimic native scar architecture and associated pathological microenvironments ...
Yao Bin, Zhu Dongzhen, Cui Xiaoli, Enhe jirigala, Song Wei, Li Zhao, Hu Tian, Zhu Ping, Li Jianjun, Wang Yuzhen, Zhang Yijie, Fu Xiaobing, Huang Sha   +12 more
doaj   +1 more source

Elucidating the role of keratin 75 in enamel using Krt75tm1Der knock-in mouse model

Frontiers in Physiology, 2022
Keratin 75 (K75) was recently discovered in ameloblasts and enamel organic matrix. Carriers of A161T substitution in K75 present with the skin condition Pseudofollicullitis barbae.
Rutuja Deshmukh, Brent Vasquez, Brent Vasquez, Lasya Bhogadi, Lasya Bhogadi, Claire M. Gabe, Claire M. Gabe, Lyudmila Lukashova, Kostas Verdelis, Kostas Verdelis, Maria I. Morasso, Elia Beniash, Elia Beniash   +12 more
doaj   +1 more source

The Therapeutic Role of ADSC-EVs in Skin Regeneration

Frontiers in Medicine, 2022
Large skin defects caused by burns, unhealing chronic wounds, and trauma, are still an intractable problem for clinicians and researchers. Ideal skin regeneration includes several intricate and dynamic stages of wound repair and regeneration of skin ...
Yixi Wang, Lihui Cheng, Hanxing Zhao, Zhengyong Li, Junjie Chen, Ying Cen, Zhenyu Zhang   +6 more
doaj   +1 more source

Stem cells and skin regeneration

Folia Histochemica et Cytobiologica, 2011
Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis. Constant regeneration of the skin is achieved due to stem cell differentiation within the epidermis and the hair follicle; thus, skin
Sylwia Słuczanowska-Głąbowska, Marzena Staniszewska, Justyna Drukała   +2 more
openaire   +4 more sources