Results 41 to 50 of about 129,837 (266)

A dopamine-methacrylated hyaluronic acid hydrogel as an effective carrier for stem cells in skin regeneration therapy

Cell Death and Disease, 2022
Adipose-derived stem cells (ADSCs) show potential in skin regeneration research. A previous study reported the failure of full-thickness skin self-repair in an injury area exceeding 4 cm in diameter. Stem cell therapies have shown promise in accelerating
Meihua Gong, Fei Yan, Li Yu, Furong Li
doaj   +1 more source

Biomimetic and Materials-Potentiated Cell Engineering for Cancer Immunotherapy

Pharmaceutics, 2022
In cancer immunotherapy, immune cells are the main force for tumor eradication. However, they appear to be dysfunctional due to the taming of the tumor immunosuppressive microenvironment.
Tingting Zhang, Yushan Yang, Li Huang, Ying Liu, Gaowei Chong, Weimin Yin, Haiqing Dong, Yan Li, Yongyong Li   +8 more
doaj   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Analysis of anatomic location of burns inpatients in China from 2009 to 2018

BMC Public Health
Background Burns cause serious physical and psychological harm to patients, placing a heavy burden on the global healthcare system. Our previous study detailed the epidemiological characteristics of burn injuries in Chinese inpatients from 2009 to 2018 ...
Jie Yang, Jianchao Liu, Kui Ma, Huajuan Bai, Mingzi Ran, Guanglei Tian, Siming Yang, Xiaobing Fu   +7 more
doaj   +1 more source

Actin cable formation and epidermis–dermis positional relationship during complete skin regeneration

Scientific Reports, 2022
Up to a certain developmental stage, a fetus can completely regenerate wounds in the skin. To clarify the mechanism of fetal skin regeneration, identifying when the skin switches from fetal-type wound regeneration to adult-type wound repair is necessary.
Kento Takaya, Keisuke Okabe, Ayaka Ishigami, Yuka Imbe, Hideko Kanazawa, Shigeki Sakai, Noriko Aramaki-Hattori, Kazuo Kishi   +7 more
doaj   +1 more source

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Treat Cutaneous Nerve Damage and Promote Wound Healing

Frontiers in Cellular Neuroscience, 2022
Wound repair is a key step in the treatment of skin injury caused by burn, surgery, and trauma. Various stem cells have been proven to promote wound healing and skin regeneration as candidate seed cells.
Ziying Zhu, Ziying Zhu, Xiaona Zhang, Haojie Hao, Heran Xu, Jun Shu, Qian Hou, Qian Hou, Min Wang   +8 more
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Biodegradable and Recyclable Luminescent Mixed‐Matrix‐Membranes, Hydrogels, and Cryogels based on Nanoscale Metal‐Organic Frameworks and Biopolymers

Advanced Functional Materials, EarlyView.
The study presents biodegradable and recyclable mixed‐matrix membranes (MMMs), hydrogels, and cryogels using luminescent nanoscale metal‐organic frameworks (nMOFs) and biopolymers. These bio‐nMOF‐MMMs combine europium‐based nMOFs as probes for the status of the materials with the biopolymers agar and gelatine and present alternatives to conventional ...
Moritz Maxeiner, Julian Burkhart, Kateryna Borysova, Chiara Mazzariol, Klaus Müller‐Buschbaum   +4 more
wiley   +1 more source

Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration

Military Medical Research
Scar formation resulting from burns or severe trauma can significantly compromise the structural integrity of skin and lead to permanent loss of skin appendages, ultimately impairing its normal physiological function.
Ying-Ying Li, Shuai-Fei Ji, Xiao-Bing Fu, Yu-Feng Jiang, Xiao-Yan Sun   +4 more
doaj   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

YAP promotes the healing of ischemic wounds by reducing ferroptosis in skin fibroblasts through inhibition of ferritinophagy

Heliyon
The impaired healing of chronic wounds is often attributed to the ischemic and hypoxic microenvironment, leading to increased cell death. Ferroptosis, a novel form of cell death unveiled in recent years, could potentially be linked with the process of ...
Guoqi Cao, Siyuan Yin, Jiaxu Ma, Yongpan Lu, Ru Song, Zhenjie Wu, Chunyan Liu, Jian Liu, Peng Wu, Rui Sun, Aoyu Chen, Yibing Wang   +11 more
doaj   +1 more source