Results 51 to 60 of about 2,543,915 (328)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Human organ rejuvenation by VEGF-A: Lessons from the skin

, 2022
Transplanting aged human skin onto young SCID/beige mice morphologically rejuvenates the xenotransplants. This is accompanied by angiogenesis, epidermal repigmentation, and substantial improvements in key aging-associated biomarkers, including ß ...
Keren, Aviad, Keren, Yaniv, Gilhar, Amos, Paus, Ralf, Ullmann, Yehuda, Bertolini, Marta   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

An investigation into the cellular mechanisms underlying photodynamic rejuvenation in human skin [PDF]

, 2012
Includes abstract.Includes bibliographical references.Photodynamic Rejuvenation (PDR) is a novel therapy used to treat the signs of skin ageing. It is a promising dermatological therapy due to its less severe side effects and superior results when ...
Van Kets, Victoria Louise
core   +1 more source

Peran Hyaluronic Acid untuk Skin Rejuvenation [PDF]

Background: As you get older, some cells in the body experience a decrease in the amount of production, including hyaluronic acid. Hyaluronan or hyaluronic acid (HA) is a molecule involved in skin moisture.
Nabila, Iffah, Triastuti, Nenny, Primadina, Nova, Srihartati, Enik   +3 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Expert Consensus on Clinical Recommendations for Fractional Ablative CO2 Laser, in Facial Skin Rejuvenation Treatment

Lasers in Surgery and Medicine
For three decades, fractional ablative CO2 lasers have been used for skin rejuvenation. With breakthroughs in laser technology and expanding popularity, new recommendations and suggestions arise on a regular basis.
Tal Levy, Ilana Lerman, Jill S Waibel, G. Gauglitz, M. T. Clementoni, Daniel P. Friedmann, Kevin Duplechain, P. Peng, Davin Lim, F. Al-Niaimi, Shangli Lin, G. Munavalli, B. Biesman, Greg J. Goodman, A. Fratila, Thomas M. Beachkofsky, E. V. Ross, Asiff Hussein, A. Kauvar, S. Kilmer, R. Langdon, Ronald L. Moy, O. Artzi   +22 more
semanticscholar   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Exploring the Safety and Efficacy of Organic Light-Emitting Diode in Skin Rejuvenation and Wound Healing

Yonsei medical journal
Purpose Photobiomodulation (PBM), encompassing low-energy laser treatment and light-emitting diode (LED) phototherapy, has demonstrated positive impacts on skin rejuvenation and wound healing.
Young-In Lee, Sang Gyu Lee, S. Ham, I. Jung, Jangmi Suk, Ju-Hee Lee   +5 more
semanticscholar   +1 more source

In vivo study of the effects of a portable cold plasma device and vitamin C for skin rejuvenation

Scientific Reports, 2021
Nowadays, cold atmospheric plasma shows interesting results in dermatology. In the present study, a new portable cold plasma was designed for plasma skin rejuvenation (PSR) purposes. This device is safe and easy to use at beauty salons and homes.
R. Shakouri, M. Khani, Shirin Samsavar, Mahya Aminrayai Jezeh, F. Abdollahimajd, S. I. Hosseini, A. Dilmaghanian, E. Ghasemi, M. Alihoseini, B. Shokri   +9 more
semanticscholar   +1 more source