Results 61 to 70 of about 2,543,915 (328)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Skin rejuvenation and photoaging protection using adipose‐derived stem cell extracellular vesicles loaded with exogenous cargos

Skin research and technology
Small extracellular vesicles from adipose‐derived stem cells (ASC‐sEVs) have gained remarkable attention for their regenerative and protective properties against skin aging.
Diem D N Nguyen, Diem My Vu, N. Vo, N. H. Tran, Duyen T. K. Ho, T. Nguyen, T. Nguyễn, Hoai-Nghia Nguyen, Lan N. Tu   +8 more
semanticscholar   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Laser Emission at 675 nm: Molecular Counteraction of the Aging Process

Biomedicines
Background/Objectives: Many lasers applied in skin rejuvenation protocols show emissions with wavelengths falling in the red or near-infrared (NIR) bands.
Lorenzo Notari, Laura Pieri, Francesca Cialdai, Irene Fusco, Chiara Risaliti, Francesca Madeddu, Stefano Bacci, Tiziano Zingoni, Monica Monici   +8 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The FEDBD plasma’s quantitative investigation of skin parameters: Skin elasticity, thickness, density, tissue oxygenation, perfusion, and edema

Heliyon
This study used the FEDBD plasma device for skin rejuvenation in animal samples. There were two groups of six male Wistar rats. Before starting the treatment, immediately after the treatment, the fourth week, and the tenth week of follow-up, biometric ...
Parisa Charipoor, Mohammad Ali Nilforoushzadeh, Mohammadreza Khani, Maryam Nouri, Erfan Ghasemi, Mohammad Amir Amirkhani, Mohammad Eftekhari, Babak Shokri   +7 more
doaj   +1 more source

Aging Skin: Nourishing from Out-In. Lessons from Wound Healing [PDF]

, 2015
Skin lesion therapy, peculiarly in the elderly, cannot be isolated from understanding that the skin is an important organ consisting of different tissues.
ROMANO, Claudia, Pinna, Raimondo, Vincenzo Flati, Giovanni Corsetti, Francesco S. Dioguardi, Claudia Romano, Raimondo Pinna, Rufo, Anna, Flati, Vincenzo, PASINI, Evasio, Anna Rufo, CORSETTI, Giovanni, Dioguardi, Francesco S., Evasio Pasini   +13 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Skin Rejuvenation by Modulation of DNA Methylation

Experimental Dermatology
Skin aging is driven by a complex set of cellular pathways. Among these, epigenetic mechanisms have garnered particular attention, because of their sensitivity to environmental and lifestyle factors.
E. Grönniger, Heiner Max, F. Lyko
semanticscholar   +1 more source

Intense Pulsed Light and Red Light Photo Rejuvenation for Skin Rejuvenation: A Split Face Clinical Trial [PDF]

, 2011
INTRODUCTION: Intense pulsed light (IPL) has long been used for skin rejuvenation. Photo rejuvenation with red light (with or without photo sensitizer) is a newer noninvasive way for this purpose; but, until now few comparative studies between these ...
Moravvej, Hamideh, Saeedi, Mohammad
core