Results 71 to 80 of about 2,543,915 (328)

Laser therapy and gene expression in skin rejuvenation

, 2023
Laser therapy, both ablative and non-ablative, plays an important role in skin rejuvenation, initiating extracellular matrix breakdown and promoting the formation of a structured matrix with sustained collagen stimulation. Ablative lasers, in particular,
Rauwenhoff, M., Verstraeten, V. L.R.M.
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Exploring the synergistic effects of poly-l-lactic acid (Sculptra®) and retinoic acid (tretinoin) in facial rejuvenation treatment for age-related skin laxity

Pakistan Journal of Pharmaceutical Sciences
To investigate the synergistic effects of Poly-L-Lactic Acid (PLLA) and Retinoic Acid (RA) on age-related skin relaxation in the treatment of facial rejuvenation. 120 patients received facial rejuvenation treatment at Sin-An Cosmetic Clinic Hospital from
Kuo-Liang Liao, Kuo-Hsiang Liao
doaj   +1 more source

Subcutaneous Injections of Nanofat Adipose-derived Stem Cell Grafting in Facial Rejuvenation

Plastic and Reconstructive Surgery, Global Open, 2020
Background:. We aimed to assess whether our novel Nanofat grafting procedure improves skin quality while yielding a regenerative effect and whether this novel technique can also achieve a lifting effect. Methods:.
Sophie Menkes, MD, Mariotta Luca, PhD, Gianni Soldati, PhD, Luigi Polla, PhD   +3 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

SKIN REJUVENATION IN OLDER ADULTS

Anti-Aging Eastern Europe
SKIN REJUVENATION IN OLDER ...
Ilke Coskun Benlidayi
doaj   +1 more source

Real‐World Experience Using a Multi‐Modality System using Intense Pulsed Light, Radiofrequency Microneedling, High‐Intensity Focused Ultrasound, or Thermal Radiofrequency, 808, HIFU for Skin Rejuvenation Treatment

Journal of Cosmetic Dermatology
Medical aesthetic procedures for facial rejuvenation with laser and energy‐based devices (EBDs) are rapidly increasing. The following cases highlight real‐life experience using a multi‐modality system with various handpieces that combine intense pulsed ...
M. Gold, B. Biesman, Joel L. Cohen, D. Goldberg, S. Guénin, Todd Schlesinger, Z. Taher   +6 more
semanticscholar   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Transcriptomic analysis of human skin wound healing and rejuvenation following ablative fractional laser treatment.

PLoS ONE, 2021
Ablative fractional laser treatment is considered the gold standard for skin rejuvenation. In order to understand how fractional laser works to rejuvenate skin, we performed microarray profiling on skin biopsies to identify temporal and dose-response ...
Joseph D Sherrill, Deborah Finlay, Robert L Binder, Michael K Robinson, Xingtao Wei, Jay P Tiesman, Michael J Flagler, Wenzhu Zhao, Catherine Miller, Jean M Loftus, Alexa B Kimball, Charles C Bascom, Robert J Isfort   +12 more
doaj   +1 more source