Results 131 to 140 of about 69,829 (286)

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

Spectroscopic and In Silico Determination of the Structural and Antioxidant Properties of Essential Oils From Lavandula Species Cultivated in the Silivri Region of Istanbul

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Plants are important sources of bioactive compounds that contribute to nutrition, health maintenance, and disease prevention. In this study, the chemical composition and antioxidant potential of essential oils obtained from Lavandula angustifolia “Sevtopolis” and Lavandula × intermedia cultivated in the Silivri region of Istanbul were ...
Bilge Bicak, Beray Kizilkaya, Serda Kecel Gunduz, Aliye Demet Demirag, Sabriye Percin Ozkorucuklu   +4 more
wiley   +1 more source

Skin Prick Testing in a Portuguese Pediatric Population: A Multicenter Cross-Sectional Study of Clinical and Allergen Sensitization Profiles

Acta Médica Portuguesa
Introduction: Allergic diseases, particularly allergic rhinitis and asthma are highly prevalent among children and adolescents and frequently associated with sensitization to inhalant allergens.
Manuel Lima Ferreira, João Nogueira Oliveira, Mariana Pinto, Arménia Oliveira, Paulo Guimarães, Aida Azevedo, Filipa Almeida, Fernanda Carvalho, Inês Falcão, Maria José Dinis, Conceição Silva, Rita S. Pereira, Raquel S. Santos, Márcia Quaresma, André Assunção, Diana Bordalo, Sylvia Jacob, David Gomes, Hunilla Jacinto, António Bento Guerra, Sofia Guedes, Patrícia Silva, Daniela Henriques, Armandina Silva, Marta Santalha, Teresa São Simão, Inês Eiras, Mariana Santos Nobre, Helena Ramalho, Rita Salgueiro, Lara Torres, Pedro Guerra, Rita Barroca, Ana Luísa Correia, Georgeta Oliveira, Rita Lages Pereira, Fábia Carvalho, Margarida Reis Morais, Diana S. Pinto, Ana Rita Araújo, Mafalda Moreira, Sandra Teixeira   +41 more
doaj   +1 more source

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source

Use of Genotoxicity Information in the Development of Integrated Testing Strategies (ITS) for Skin Sensitization

, 2016
Skin sensitization is an end point of concern for various legislation in the EU, including the seventh Amendment to the Cosmetics Directive and Registration Evaluation, Authorisation and Restriction of Chemicals (REACH).
E Maria Donner (2258596), Stoyanka Stoeva (2112457), Milen Todorov (2258599), Gergana Dimitrova (2258593), Ovanes Mekenyan (1845154), Grace Patlewicz (1845178), Chanita Kuseva (1845163), Stefan Kotov (1845172)   +7 more
core   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

A Perspective and a New Integrated Computational Strategy for Skin Sensitization Assessment

, 2018
Traditionally, the skin sensitization potential of chemicals has been assessed using animal models. Due to growing ethical, political, and financial concerns, sustainable alternatives to animal testing need to be developed.
Silva, Arthur C., Hartung, Thomas, Andrade, Carolina Horta, Tropsha, Alexander, Alves, Vinicius M., Capuzzi, Stephen J., Braga, Rodolpho C., Luechtefeld, Thomas, Borba, Joyce V. B., Muratov, Eugene N.   +9 more
core   +2 more sources

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

LuSens: Shedding Light on Skin Sensitization

, 2017
Skin sensitizers or their metabolites are predominantly electrophilic molecules and have the capacity to induce the Nrf2 signalling pathway. Therefore, they trigger the expression of genes under the control of the antioxidant response element (ARE), most
Mehling, Landsiedel, Ramirez
core   +1 more source

High Dietary Salt Exposure During Sensitization Is Associated with Increased Severity of Allergic Contact Dermatitis in Mice

Allergies
Background: High dietary salt intake has been implicated in immune-mediated inflammatory diseases; however, its impact on allergic contact dermatitis (ACD) remains unclear.
Yukihiro Yoshimura, Aya Fujii
doaj   +1 more source