Results 51 to 60 of about 2,229,109 (306)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Медицинский совет, 2021 Introduction. In the context of a decrease in the tension of the epidemic situation on tuberculosis in Russia, it remains relevant to search for new ways to increase the effectiveness of preventive anti-tuberculosis measures among children and teenagers,
O. D. Baronova +4 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Risk Management and Healthcare Policy, 2023 Bo Li,1,2 Li Jiang,1,2 Ni Wu,1,2 Yao Chen,1,2 Zhi Xu,3 Fengcheng Xu,2,4 Heping Chen,1 Tianhu Liu2,4 1Clinical Pharmacy Department, The Third Affiliated Hospital of Chengdu Medical College, Pidu District People’s Hospital, Chengdu, Sichuan, People’s ...
Li B +7 more
doaj
KOLONISASI BAKTERI PATOGEN POTENSIAL PENYEBAB INFEKSI DAERAH OPERASI PADA KULIT PASIEN PRAOPERATIF [PDF]
, 2015 Backgroud : Surgical Site Infection (SSI) is associated with mortality and morbidity in hospital. The most common pathogen that caused SSI are Staphylococcus aureus, Escherichia coli, Enterobacter sp, Pseudomonas sp. , and Klebsiella sp.
Farida, Helmia +2 more
core
Difference in proton radii of mirror nuclei as a possible surrogate for the neutron skin
, 2017 It has been recently suggested that differences in the charge radii of mirror nuclei are proportional to the neutron-skin thickness of neutron-rich nuclei and to the slope of the symmetry energy $L$ [B.A. Brown Phys. Rev. Lett. 119, 122502 (2017)].
Piekarewicz, J., Yang, Junjie
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A 2.5-D representation of the human hand [PDF]
, 2012 Primary somatosensory maps in the brain represent the body as a discontinuous, fragmented set of 2-D skin regions. We nevertheless experience our body as a coherent 3-D volumetric object.
Haggard, P., Longo, Matthew R.
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Delabelling beta-lactam allergy
Frontiers in PharmacologyBackground: Hypersensitivity to beta-lactam (BL) antibiotics is one of the most frequent reported drug allergies. In our population, it is common to find labels of BL allergy in electronic medical records (EMRs) that have not been assessed. The objective
Gustavo-Jorge Molina-Molina +21 more
doaj +1 more source