Results 61 to 70 of about 2,229,109 (306)

EFFECT OF SERVICE QUALITY TO PURCHASING DECISION THROUGH BRAND TRUST AND BRAND IMAGE (Study in Gracia Skin Clinic at Semarang City) [PDF]

, 2017
This study was conducted to determine how service quality influenced consumer’s purchasing decisions, through brand image and brand trust on Gracia Skin Clinic Semarang.The result then used to take the company's policy in the future so that it can ...
ANDANAWARI, Anindya Rachma, Mahfudz, Mahfudz, SOESANTO, HARRY   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Accuracy of an artificial intelligence as a medical device as part of a UK-based skin cancer teledermatology service

Frontiers in Medicine
IntroductionAn artificial intelligence as a medical device (AIaMD), built on convolutional neural networks, has demonstrated high sensitivity for melanoma. To be of clinical value, it needs to safely reduce referral rates.
Helen Marsden, Polychronis Kemos, Marcello Venzi, Mariana Noy, Shameera Maheswaran, Nicholas Francis, Christopher Hyde, Daniel Mullarkey, Dilraj Kalsi, Lucy Thomas   +9 more
doaj   +1 more source

Horse-serum skin tests [PDF]

Journal of Hygiene, 1938
An investigation is described which shows the type of skin reaction which may be expected from the intracutaneous injection of 0·1 c.c. normal horse serum in the normal and sensitized human subject. 150 normal individuals and 100 who had received previous serum injection were skin-tested. Of the normal subjects 30% showed a reaction of skin sensitivity,
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Las pruebas epicutáneas de contacto en medicina laboral Patch testing in occupational medicine

Medicina y Seguridad del Trabajo, 2013
Dentro de la Medicina Laboral las dermatosis ocupacionales suponen entre el 30-60% del total de enfermedades profesionales y, dentro de ellas el 80-90% son dermatitis de contacto.
Carolina Granados Rincón, Nelly Machado Benavides, Ana Rita Rodrigues-Barata, Luis Conde-Salazar Gómez   +3 more
doaj  

Skin Test for Cutaneous Adverse Drug Reactions

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2020
Background: The incidence of drug eruptions is increasing during the last few years due to a large number of new medications. Early detection of the causative agent and the prevention from exposure are crucial managements in terms of drug eruption ...
Yusuf Wibisono, Damayanti Damayanti
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

EQ-5D in skin conditions: an assessment of validity and responsiveness [PDF]

, 2014
Aims and objectives This systematic literature review aims to assess the reliability, validity and responsiveness of three widely used generic preference-based measures of health-related quality of life (HRQL), i.e., EQ-5D, Health Utility Index 3 (HUI3 ...
AFN Klassen, BF O’donnell, C Moberg, D Feeny, D Papaioannou, D Revicki, DF Cella, E Christophers, E Daudén, GH Guyatt, GR Barton, J Brazier, J Brazier, J Brazier, J Dowie, J Tosh, JE Brazier, John Brazier, K Reich, L Longworth, L Longworth, L Matusiak, Louise Longworth, M Herdman, NICE, NICE, NJ Bansback, P Dolan, P Swinburn, PCM Kerkhof Van De, R Brooks, R Shikiar, R Shikiar, RJ Lasek, S Weiss, SCR Weiss, SJ Walters, T Luger, V Brodszky, Yaling Yang   +39 more
core   +3 more sources