Results 111 to 120 of about 15,177,173 (309)

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Inverse association between positive tuberculin tests and positive allergy skin tests in children

Paediatrica Indonesiana, 2009
Background  The  association between  Mycobacterium  tuberculosis infection  and  atopy remains controversial. Reaction to tuberculosis infection  is  mediated  by  Th-1  immune responses whereas allergic reactions are mediated  by  Th- 2 immune response.
Nur Rochmah, Dyahris Kuntartiwi, Anang Endaryanto, Aryanto Harsono   +3 more
doaj   +1 more source

Deep Learning for Skin Lesion Classification [PDF]

arXiv, 2017
Melanoma, a malignant form of skin cancer is very threatening to life. Diagnosis of melanoma at an earlier stage is highly needed as it has a very high cure rate. Benign and malignant forms of skin cancer can be detected by analyzing the lesions present on the surface of the skin using dermoscopic images.
arxiv  

Eosinophilia and positive skin tests predict cardiovascular mortality in a general population sample followed for 30 years.

American Journal of Epidemiology, 1999
The authors investigated whether two objective allergy markers, peripheral blood eosinophilia and skin tests for common aeroallergens, were associated with cardiovascular death. Of 5,382 subjects in the Vlagtwedde-Vlaardingen Study (the Netherlands) with
J. Hospers, B. Rijcken, J. Schouten, D. Postma, Scott T. Weiss   +4 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

WonDerM: Skin Lesion Classification with Fine-tuned Neural Networks [PDF]

arXiv, 2018
As skin cancer is one of the most frequent cancers globally, accurate, non-invasive dermoscopy-based diagnosis becomes essential and promising. A task of the Part 3 of the ISIC Skin Image Analysis Challenge at MICCAI 2018 is to predict seven disease classes with skin lesion images, including melanoma (MEL), melanocytic nevus (NV), basal cell carcinoma (
arxiv  

Pharmacist-managed service providing penicillin allergy skin tests.

American Journal of Health-System Pharmacy, 2004
PURPOSE A penicillin allergy skin-testing service run by pharmacists is described. SUMMARY A board-certified allergist trained pharmacists at a tertiary care teaching hospital to administer penicillin allergy skin tests and interpret the results.
G. Wall, Lisa K Peters, Catherine B Leaders, James A Wille   +3 more
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Use of Low Molecular Weight Antigens of Mycobacterium tuberculosis as a New Skin Test for Specific Diagnosis of Tuberculosis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019
Background and Objectives: Tuberculosis (TB) is an infectious disease and about one-third of the world population are infected with latent TB infection.
Davoud Sadeghi Gariz, Nader Mosavari
doaj  

DermGAN: Synthetic Generation of Clinical Skin Images with Pathology [PDF]

arXiv, 2019
Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly challenging. In this work, we explore the possibility of using Generative Adverserial Networks (GAN) to synthesize ...
arxiv