Results 61 to 70 of about 16,185,394 (397)

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Flexible fastener allows thermal expansion [PDF]

, 1964
A flexible fastener permits thermal expansion of model skin sections which are rigidly attached to supporting structures in wind tunnel tests.
Crumpler, W. B.
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Reversible Rail Shear Apparatus Applied to the Study of Woven Laminate Shear Behavior [PDF]

, 2013
The multitude of in-plane shear tests existing in the literature seems to demonstrate the complexity of developing a test adapted to all experimental works.
Bouvet, Christophe, Nègre, Vincent, Rauch, Patrice, Rouault, Thomas   +3 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

The state and consideration for skin test of β-lactam antibiotics in pediatrics

Frontiers in Cellular and Infection Microbiology, 2023
β-lactam antibiotics are the most frequently used drugs and the most common drugs that cause allergic reactions in pediatrics. The occurrence of some allergic reactions can be predicted by skin testing, especially severe adverse reactions such as ...
Chunhui Gao, Bowen Ma, Wei Liu, Liqin Zhu   +3 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

An investigation of the relationship between thermal imaging and digital thermometer [PDF]

, 2015
BACKGROUND: A number of research papers and theoretical clinical models summarising how temperature of the skin over the knee may be altered according to different pathological processes have been published. Thermal imaging (TI) is generally regarded as
American Society for Testing and Material (ASTM), Ammer, Bland, Coughlan, Denoble, Dye, Gold, Lavery, Menard, Naslund, Ring, Ring, Sanchis-Alfonso, Sandow, Selfe, Selfe, Selfe, Selfe, Selfe, Selfe, Tootill   +20 more
core   +1 more source

A Narrative Review on Evaluation of Causal Drug in Cutaneous Drug Eruptions: Challenges, Current State, and the Path Ahead

International Journal of Advanced Medical and Health Research
The diagnosis of cutaneous drug reactions is challenging, particularly when it involves the identification of the culprit drug. This exercise is, however, essential, as re-prescription of the offending drug is harmful to the patient while holding back an
Sivaranjini Ramassamy
doaj   +1 more source