Results 81 to 90 of about 1,376,553 (308)

Anaphylactic shock caused by an intradermal skin test-negative antibiotic during general anesthesia -A case report- [PDF]

open access: yes, 2016
Anaphylaxis during the perioperative period is rare, but it still causes severe cardiovascular and respiratory collapse that can be fatal. In particular, when using antibiotics that have a high risk of hypersensitivity reactions, it is important to ...
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core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

American cutaneous leishmaniasis: use of a skin test as a predictor of relapse after treatment

open access: yesBulletin of the World Health Organization, 2000
While relapses following clinical cure of American cutaneous leishmaniasis are frequent, no test has been described until now to predict such relapses.
Valéria M.A. Passos   +5 more
doaj  

A Narrative Review on Evaluation of Causal Drug in Cutaneous Drug Eruptions: Challenges, Current State, and the Path Ahead

open access: yesInternational Journal of Advanced Medical and Health Research
The diagnosis of cutaneous drug reactions is challenging, particularly when it involves the identification of the culprit drug. This exercise is, however, essential, as re-prescription of the offending drug is harmful to the patient while holding back an
Sivaranjini Ramassamy
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Research in Natural Laminar Flow and Laminar-Flow Control, part 2 [PDF]

open access: yes
Part 2 of the Symposium proceedings includes papers addressing various topics in basic wind tunnel research/techniques and computational transitional research.
Hefner, Jerry N., Sabo, Frances E.
core   +1 more source

Buckling of foam stabilised composite structures [PDF]

open access: yes, 2003
An analytical modelling of the symmetrical wrinkling is proposed : from original assumptions on displacements within the core, and from an energy minimisation method, it is possible to predict critical loads and buckling modes better than traditional ...
Barrau, Jean-Jacques   +2 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Histoplasmin and paracoccidioidin skin reactivity in infantile population of Northern Argentina Reatividade cutânea à histoplasmina e paracoccidioidina na população infantil do norte da Argentina

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1996
In order to estimate ages at which etiological agents of systemic mycoses initiate infection, histoplasmin and paracoccidioidin skin tests were performed in 344 children of both sexes, between 2 and 15 years old.
Magdalena Mangiaterra   +4 more
doaj   +1 more source

Ambient temperature fatigue tests of elements of an actively cooled honeycomb sandwich structural panel [PDF]

open access: yes
Elements of an actively cooled structural panel for a hypersonic aircraft have been investigated for fatigue characteristics. The study involved a bonded honeycomb sandwich panel with d-shaped coolant tubes. The curved portion of these tubes was embedded
Elber, W., Sharpe, E. L.
core   +1 more source

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