Results 1 to 10 of about 341,517 (311)

The frog skin-derived antimicrobial peptide esculentin-1a(1-21)nh2 promotes the migration of human hacat keratinocytes in an egf receptor-dependent manner: a novel promoter of human skin wound healing? [PDF]

, 2015
One of the many functions of skin is to protect the organism against a wide range of pathogens. Antimicrobial peptides (AMPs) produced by the skin epithelium provide an effective chemical shield against microbial pathogens. However, whereas antibacterial/
Cappiello, Floriana, DI GRAZIA, Antonio, Imanishi, Akiko, Mangoni, Maria Luisa, Mastrofrancesco, Arianna, Paus, Ralf, Picardo, Mauro   +6 more
core   +9 more sources

Cluster analysis identifies six clinical subtypes of hidradenitis suppurativa characterised by distinct comorbidities, inflammatory and metabolic profiles, patient‐reported outcomes and treatment patterns

JEADV Clinical Practice, 2023
Background Sub‐classification of hidradenitis suppurativa (HS) may allow for a better understanding of disease aetiology and disease burden, and eventually permit a more personalised treatment for patients.
Astrid‐Helene R. Jørgensen, Nicolai S. Arildsen, Yiqiu Yao, Jesper G. Holm, Valdemar W. Nielsen, Hans C. Ring, Anders Woetmann, Simon F. Thomsen   +7 more
doaj   +1 more source

Reversibly immortalized keratinocytes (iKera) facilitate re-epithelization and skin wound healing: Potential applications in cell-based skin tissue engineering

Bioactive Materials, 2022
Skin injury is repaired through a multi-phase wound healing process of tissue granulation and re-epithelialization. Any failure in the healing process may lead to chronic non-healing wounds or abnormal scar formation.
Jiamin Zhong, Hao Wang, Ke Yang, Huifeng Wang, Chongwen Duan, Na Ni, Liqin An, Yetao Luo, Piao Zhao, Yannian Gou, Shiyan Sheng, Deyao Shi, Connie Chen, William Wagstaff, Bryce Hendren-Santiago, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Sherwin H. Ho, Guillermo A. Ameer, Le Shen, Tong-Chuan He, Jiaming Fan   +22 more
doaj   +1 more source

Applications of MXene and its modified materials in skin wound repair

Frontiers in Bioengineering and Biotechnology, 2023
The rapid healing and repair of skin wounds has been receiving much clinical attention. Covering the wound with wound dressing to promote wound healing is currently the main treatment for skin wound repair.
Ziyan Zhang, Zhiping Qi, Weijian Kong, Renfeng Zhang, Chunli Yao   +4 more
doaj   +1 more source

The Bigger Picture: Why Oral Mucosa Heals Better Than Skin

Biomolecules, 2021
Wound healing is an essential process to restore tissue integrity after trauma. Large skin wounds such as burns often heal with hypertrophic scarring and contractures, resulting in disfigurements and reduced joint mobility.
Maaike Waasdorp, Bastiaan P. Krom, Floris J. Bikker, Paul P. M. van Zuijlen, Frank B. Niessen, Susan Gibbs   +5 more
doaj   +1 more source

Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing

Nature Communications, 2020
Diabetic foot ulcers (DFU) represent a complex disease with limited treatment options. Here, the authors compare human RNASeq patient data from DFU, oral mucosa and skin acute wounds, identifying FOXM1 as a mediator of macrophage and neutrophil ...
Andrew P. Sawaya, Rivka C. Stone, Stephen R. Brooks, Irena Pastar, Ivan Jozic, Kowser Hasneen, Katelyn O’Neill, Spencer Mehdizadeh, Cheyanne R. Head, Natasa Strbo, Maria I. Morasso, Marjana Tomic-Canic   +11 more
doaj   +1 more source

Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds. [PDF]

, 2020
Chronic wounds represent a large and growing disease burden. Infection and biofilm formation are two of the leading impediments of wound healing, suggesting an important role for the microbiome of these wounds.
Chen, Irene A, Deacon, John M, Lee, Juhee, Shen, Yuning, Verbanic, Samuel   +4 more
core   +1 more source

Scar-Free Healing: Current Concepts and Future Perspectives

Nanomaterials, 2020
Every year, millions of people develop scars due to skin injuries after trauma, surgery, or skin burns. From the beginning of wound healing development, scar hyperplasia, and prolonged healing time in wound healing have been severe problems. Based on the
Alexandra Elena Stoica, Alexandru Mihai Grumezescu, Anca Oana Hermenean, Ecaterina Andronescu, Bogdan Stefan Vasile   +4 more
doaj   +1 more source

IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin

Frontiers in Immunology, 2022
IntroductionAlthough the presence of pathogens in skin wounds is known to delay the wound healing process, the mechanisms underlying this delay remain poorly understood.
Jean-Claude Lecron, Jean-Claude Lecron, Sandrine Charreau, Sandrine Charreau, Jean-François Jégou, Nadjet Salhi, Isabelle Petit-Paris, Emmanuel Guignouard, Christophe Burucoa, Christophe Burucoa, Laure Favot-Laforge, Charles Bodet, Anne Barra, Anne Barra, Vincent Huguier, Vincent Huguier, Jiad Mcheik, Jiad Mcheik, Laure Dumoutier, Julien Garnier, François-Xavier Bernard, François-Xavier Bernard, Bernhard Ryffel, Franck Morel   +23 more
doaj   +1 more source

The Importance of Hydration in Wound Healing: Reinvigorating the clinical perspective [PDF]

, 2016
Balancing skin hydration levels is important as any disruption in skin integrity will result in disturbance of the dermal water balance. The discovery that a moist wound healing environment actively supports the healing response when compared to a dry ...
Atiyeh B.S., Atiyeh B.S., Eaglstein W.H., Faria D., Gabriel A., Gabriel A., Gray D., Hebra F., Leung B.K., Park A.C., Rubio P.A., Scheuplein R., Verdier-Sévrain S., Xu W., Zelen C.M.   +14 more
core   +1 more source