Results 11 to 20 of about 341,517 (311)

Organoids in skin wound healing. [PDF]

Burns Trauma
Abstract Stem cells (SCs) can self-replicate and differentiate into multiple lineages. Organoids, 3D cultures derived from SCs, can replicate the spatial structure and physiological characteristics of organs in vitro. Skin organoids can effectively simulate the physiological structure and function of skin tissue, reliably restoring the ...
Wang Z, Zhao F, Lang H, Ren H, Zhang Q, Huang X, He C, Xu C, Tan C, Ma J, Duan S, Wang Z.   +11 more
europepmc   +3 more sources

Extracellular Vesicles in Skin Wound Healing [PDF]

Pharmaceuticals, 2021
Each year, millions of individuals suffer from a non-healing wound, abnormal scarring, or injuries accompanied by an infection. For these cases, scientists are searching for new therapeutic interventions, from which one of the most promising is the use of extracellular vesicles (EVs).
Deimantė Narauskaitė, Gabrielė Vydmantaitė, Justina Rusteikaitė, Revathi Sampath, Akvilė Rudaitytė, Gabija Stašytė, María Isabel Aparicio Calvente, Aistė Jekabsone   +7 more
openaire   +3 more sources

Autophagy and skin wound healing

Burns & Trauma, 2022
Abstract Autophagy is a lysosome-dependent, self-renewal mechanism that can degrade and recycle cellular components in eukaryotic cells to maintain the stability of the intracellular environment and the cells ability to cope with unfavorable environments. Numerous studies suggest that autophagy participates in regulating various cellular
Haiyue Ren, Feng Zhao, Qiqi Zhang, Xing Huang, Zhe Wang   +4 more
openaire   +2 more sources

Eicosanoids in Skin Wound Healing

International Journal of Molecular Sciences, 2020
Wound healing is an important process in the human body to protect against external threats. A dysregulation at any stage of the wound healing process may result in the development of various intractable ulcers or excessive scar formation. Numerous factors such as growth factors, cytokines, and chemokines are involved in this process and play vital ...
Ken Yasukawa, Toshiaki Okuno, Takehiko Yokomizo   +2 more
openaire   +2 more sources

Skin wound healing as a mirror to cardiac wound healing

Experimental Physiology, 2023
AbstractWound healing is a general response of the body to injury. All organs share in common three response elements to wound healing: inflammation to prevent infection and stimulate the removal of dead cells, active anti‐inflammatory signalling to turn off the inflammatory response, and a repair phase characterized by extracellular matrix scar ...
Merry L. Lindsey, Mediha Becirovic‐Agic   +1 more
openaire   +4 more sources

Wound Healing and Skin Regeneration [PDF]

Cold Spring Harbor Perspectives in Medicine, 2015
The skin is a complex organ consisting of the epidermis, dermis, and skin appendages, including the hair follicle and sebaceous gland. Wound healing in adult mammals results in scar formation without any skin appendages. Studies have reported remarkable examples of scarless healing in fetal skin and appendage regeneration in adult skin following the ...
Makoto, Takeo, Wendy, Lee, Mayumi, Ito
openaire   +2 more sources

Effect of natural-based biological hydrogels combined with growth factors on skin wound healing

Nanotechnology Reviews, 2022
Skin wound healing is a continuous and complex process affected by many factors. Growth factors play an important role in the process of wound healing. Local application of growth factors can significantly promote wound healing.
Wang Feng, Gao Yu, Li Hao, Zhou Lihui, Shi Huijing, Feng Sining, Chen Jing, Mei Ziqing   +7 more
doaj   +1 more source

Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model : experimental study [PDF]

, 2019
Objective: Full-thickness cutaneous wounds treated with split-thickness skin grafts often result in unaesthetic and hypertrophic scars. Dermal substitutes are currently used together with skin grafts in a single treatment to reconstruct the dermal layer ...
Amos, Anderson, Banyard, Blanton, Blecher, Cao, Davis, de Vries, Dominici, Foltynski, Foubert, Greenhalgh, Hendrickx, Holder, Huang, Jang, Kataoka, Kilkenny, Kilroy, Kim, Koh, Lu, Michaels, Moon, Nambu, Nguyen, Nie, Nie, Pirayesh, Rasband, Rowan, Seo, Sivan, Truong, Tsuboi, Wainwright, Wang, Zannettino   +37 more
core   +2 more sources

Rational Design and Preparation of Functional Hydrogels for Skin Wound Healing

Frontiers in Chemistry, 2022
Skin wound healing often contains a series of dynamic and complex physiological healing processes. It is a great clinical challenge to effectively treat the cutaneous wound and regenerate the damaged skin.
Ruinan Hao, Zhuoyi Cui, Xindan Zhang, Ming Tian, Liqun Zhang, Liqun Zhang, Feng Rao, Feng Rao, Jiajia Xue, Jiajia Xue   +9 more
doaj   +1 more source

Marrow-derived stromal cell delivery on fibrin microbeads can correct radiation-induced wound-healing deficits. [PDF]

, 2013
Skin that is exposed to radiation has an impaired ability to heal wounds. This is especially true for whole-body irradiation, where even moderate nonlethal doses can result in wound-healing deficits.
Gaberman, Elena, Gorodetsky, Raphael, Levdansky, Lilia, Mackenzie, Natalia C, McBride, William H, Micewicz, Ewa D, Xie, Michael W   +6 more
core   +1 more source