Stem Cell Research & Therapy, 2018 Background Patients with a deep burn injury are characterized by losing the function of perspiration and being unable to regenerate the sweat glands. Because of their easy accession, multipotency, and lower immunogenicity, bone marrow-derived mesenchymal
Sujing Sun +6 more
doaj +1 more source
Journal of Translational Medicine, 2022 Background Radiation-induced skin injury is a well-known risk factor for impaired wound healing. Over time, the deleterious effects of radiation on skin produce a fibrotic, hypovascular dermis poorly suited to wound healing.
Hendrik Lintel +10 more
doaj +1 more source
Epidermal grafting versus split-thickness skin grafting for wound healing (EPIGRAAFT): study protocol for a randomised controlled trial [PDF]
, 2016 BACKGROUND: Split-thickness skin grafting (SSG) is an important modality for wound closure. However, the donor site becomes a second, often painful wound, which may take more time to heal than the graft site itself and holds the risk of infection and ...
Afshin Mosahebi +5 more
core +5 more sources
Research on Strategies for Wound Healing and Infection Control in Skin Disease Nursing [PDF]
SHS Web of ConferencesThe skin, as the largest organ in the human body, plays multiple roles such as protecting, sensing, and regulating body temperature. Wound healing and infection control are two extremely important links, in the treatment and care of skin diseases ...
Yang Xiaoyu
doaj +1 more source
Systemic and topical administration of spermidine accelerates skin wound healing
Cell Communication and Signaling, 2021 Background The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/uPA ...
Daisuke Ito +5 more
doaj +1 more source
Exploitation of Skin Microbiota in Wound Healing: Perspectives During Space Missions
Frontiers in Bioengineering and Biotechnology, 2022 Wound healing is slowed in Space. Microgravity and possible physical factors associated with Space affect alterations in fibroblast, matrix formation, dysregulation in apoptosis and inflammation.
Massimiliano Marvasi +3 more
doaj +1 more source
A multiscale hybrid mathematical model of epidermal-dermal interactions during skin wound healing. [PDF]
, 2019 Following injury, skin activates a complex wound healing programme. While cellular and signalling mechanisms of wound repair have been extensively studied, the principles of epidermal-dermal interactions and their effects on wound healing outcomes are ...
Chen, Weitao +7 more
core +1 more source
Platelet-derived transforming growth factor-β1 promotes keratinocyte proliferation in cutaneous wound healing. [PDF]
, 2020 Platelets are a recognised potent source of transforming growth factor-β1 (TGFβ1), a cytokine known to promote wound healing and regeneration by stimulating dermal fibroblast proliferation and extracellular matrix deposition.
Chong, DLW +7 more
core +3 more sources
Conductive Biomaterials as Bioactive Wound Dressing for Wound Healing and Skin Tissue Engineering
Nano-Micro Letters, 2021 Conductive biomaterials based on conductive polymers, carbon nanomaterials, or conductive inorganic nanomaterials demonstrate great potential in wound healing and skin tissue engineering, owing to the similar conductivity to human skin, good antioxidant ...
Rui Yu, Hualei Zhang, Baolin Guo
doaj +1 more source
Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. [PDF]
, 2014 Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined.
Byrne, Barbara A +7 more
core +2 more sources