Results 51 to 60 of about 341,517 (311)
JEADV Clinical PracticeBackground Patients suffering from chronic spontaneous urticaria (CSU) are typically classified as type I or type IIb autoimmune CSU, but further patient stratification is hindered by the lack of biomarkers.
Katrine Baumann +6 more
doaj +1 more source
Exploring a role for regulatory miRNAs in wound healing during ageing: involvement of miR-200c in wound repair [PDF]
, 2017 YesMultiple factors and conditions can lead to impaired wound healing. Chronic non-healing wounds are a common problem among the elderly. To identify microRNAs negatively impacting the wound repair, global miRNA profiling of wounds collected from young
Ahmed, Mohammed I. +4 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Stem Cells Translational Medicine, 2020 Skin is the largest organ of the human body. Skin wound is one of the most common forms of wound. Mesenchymal stromal cells (MSCs) have been used to aid skin wound healing via their paracrine factors. Because the secretome of MSCs can be greatly enriched
Mengting Zhu +13 more
doaj +1 more source
Local Drug Delivery Strategies towards Wound Healing
Pharmaceutics, 2023 A particular biological process known as wound healing is connected to the overall phenomena of growth and tissue regeneration. Several cellular and matrix elements work together to restore the integrity of injured tissue.
Ruchi Tiwari, Kamla Pathak
doaj +1 more source
Expression of hepatocyte growth factor-like protein in human wound tissue and its biological functionality in human keratinocytes [PDF]
, 2015 Hepatocyte growth factor-like protein (HGFl) and its receptor, Recepteur d'Origine Nantais (RON), have been implicated in the development of wound chronicity.
Bosanquet, David C. +5 more
core +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2021 Keratinocyte proliferation and migration are crucial steps during skin wound healing. The functional role of microRNAs (miRs) remains relatively unknown during this process.
Xiao Feng +3 more
doaj +1 more source
Modelling strategies for the healing of burn wounds [PDF]
, 2007 Epidermal wound healing requires the coordinated involvement of complex cellular and biochemical processes. In the case of epidermal wounds associated with burns, the healing process may be less than optimal and may take a significant amount of time ...
Denman, Paula Kerri
core +1 more source
MicroRNAs in skin and wound healing
Physiological Genomics, 2011 MicroRNAs (miRNAs) are small endogenous RNA molecules ∼22 nt in length. miRNAs are capable of posttranscriptional gene regulation by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation or suppression of translation. miRNAs have recently been shown to play pivotal roles in skin development and are linked to various skin ...
Jaideep, Banerjee +2 more
openaire +3 more sources