Results 51 to 60 of about 4,746,716 (297)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Vascularized anterolateral thigh free flap for salvage reconstruction of complex anterior skull base and nasion defects after failed conventional reconstruction— how I do it

Acta Neurochirurgica
Background Sinonasal inverted papilloma (SNIP) is histologically benign but locally aggressive, with high recurrence rates and a relevant risk of malignant transformation.
Hongjun Liu, Felix Knapp, Jörg Schipper, Katharina Faust, Sajjad Muhammad   +4 more
doaj   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Benefits of skull base surgery using neuronavigation system [PDF]

, 2008
Objective : Skull base tumors frequently encase or extend into vital neurovascular structures. Preoperative planning and intraoperative identification of anatomic landmarks is important in complex tumors since it helps avoid or minimize surgical ...
안정용, 박영목, 장종희, 심유식   +3 more
core  

Reconstructive aspects in anterior skull base surgery

, 2009
The treatment of malignancies of the anterior skull base is a coordinated multi-specialty approach that combines neurosurgery, otorhinolaryngology and oral and maxillofacial surgery.
Neukam, FW, Nkenke, E, Fenner, M
core   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

Porous polyethylene implant for cranioplasty and skull base reconstruction [PDF]

, 2004
journal articleObject. Cranial reconstruction after skull base surgery is important for restoration of function and cosmesis. The authors describe their experience with the Medpor porous polyethylene implant for cosmetic cranioplasty and reconstruction ...
Couldwell, William T., Liu, James K.; Gottfried, Oren N.; Cole, Chad D.; Dougherty, William R.   +1 more
core   +2 more sources

Advances in Reconstruction of the Skull Base [PDF]

Current Otorhinolaryngology Reports, 2013
Reconstruction of the skull base continues to advance at an exponentially rapid rate. New methods of vascular tissue mobilization, improvement in technology, and advancement in minimally invasive tissue harvesting allow for multiple endoscopic reconstruction options of the anterior skull base.
Rounak B. Rawal, Emily C. Ambrose, Mihir R. Patel, Adam M. Zanation   +3 more
openaire   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Simultaneous repair of bilateral temporal bone meningoencephaloceles by combined mastoid-middle cranial fossa approach

Acta Oto-Laryngologica Case Reports, 2023
Meningoencephalocele (MEC) is a rare clinical entity caused by herniation of the dura mater and brain tissue through bony defects in the skull base. We herein report a case of bilateral MECs found after recurrent bacterial meningitis.
Kazuto Osaka, Takayuki Okano, Masahiro Tanji, Koichi Omori   +3 more
doaj   +1 more source