Results 71 to 80 of about 4,746,716 (297)

Investigation of the reasons and management of repair failure of high-flow cerebrospinal fluid rhinorrhea after endoscopic removal of skull base tumors

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To investigate the reasons and management of repair failure of high-flow cerebrospinal fluid rhinorrhea (HFCSFR) after endoscopic resection of skull base tumors. Methods We retrospectively reviewed 5 patients with repair failure of HFCSFR after
Xiao-li MENG, Jing-hai WAN
doaj  

Temporalis Fascia and Free Post‐Aural Soft Tissue Graft in Sub‐Centimeter Skull Base Defect Repair [PDF]

Journal of Rhinology
Skull base defects often manifest as meningocele/meningoencephalocele or cerebrospinal fluid (CSF) leaks. Ventral and lateral skull base defects are effectively treated endoscopically and microscopically using various approaches.
Vijay Bidkar, Khadeeja K
doaj   +1 more source

Treatment of Cerebrospinal Fluid leakage in Skull Base Surgery [PDF]

, 2008
Objective : In various skull base approaches, the risk of cerebrospinal fluid (CSF) leakage exists and the leakage may lead to a life-threatening condition such as meningoencephalitis.
안정용, 장종희, 이규성, 홍창기, 심유식   +4 more
core  

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

Vascularized flap versus free graft in anterior skull base reconstruction in cases of unilateral CSF rhinorrhea [PDF]

Al-Azhar International Medical Journal
Background: Cerebrospinal fluid (CSF) rhinorrhea is an abnormal communication between the subarachnoid space and the nasal cavity. Its causes can be traumatic or non-traumatic.
Hesham Korkor, mohammad Al-Morsy, abdelaziz saad   +2 more
doaj   +1 more source

Comprehensive Techniques in CSF Leak Repair and Skull Base Reconstruction /

, 2013
Written by international leading experts in the field of skull base surgery, this publication provides a comprehensive description of both the etiology and management of defects arising in the anterior skull base.
Bleier, B.S.
core  

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Advance on endoscopic skull base surgery

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Endoscopic skull base surgery started from 1990s, and has undergone fast development in the past 20 years. It has involved various skull base regions from the anterior skull base to the craniovertebral junction (CVJ) and jugular foramen, including intra-
Qiu-hang ZHANG
doaj  

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source