Results 171 to 180 of about 76,636 (292)

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Tracking persistent and resistant Enterococcus faecalis and E. faecium from farm to fork: biofilm-linked risks in antibiotic resistance of isolates. [PDF]

Vet Res Commun
Koskeroglu K, Onmaz NE, Gundog DA, Gungor C, Gungor G, Imre K, Morar A.   +6 more
europepmc   +1 more source

Homo luzonensis and the role of homoplasy in the morphology of hominin insular species

Cladistics, EarlyView.
Abstract Homo luzonensis lived during the upper Pleistocene in the northern Philippines, east of the Wallace line. The few specimens attributed to this species show a mosaic of plesiomorphies for the genus Homo and apomorphies found in upper Pleistocene Homo species.
Pierre Gousset, Jérémie Bardin, Isabelle Rouget, Armand S. Mijares, Florent Détroit   +4 more
wiley   +1 more source

Molecular epidemiology and genetic relatedness of zoonotic Campylobacter species from human and food-producing animal sources in Enugu State, Nigeria. [PDF]

Sci Rep
Njoga EO, Chah KF, Oguttu JW.
europepmc   +1 more source

A review of the literature: Gender, food safety and the pork value chain in Vietnam [PDF]

, 2020
Mitchell, Marisa E.V.
core  

Sustainable control of cyathostomin infections in practice

Equine Veterinary Education, EarlyView.
Summary Cyathostomins are the most prevalent helminths in horses and are found in nearly all grazing groups. These parasites have been shown to exhibit widespread anthelmintic resistance and can cause clinical disease, so they are a growing concern.
J. B. Matthews, T. S. Mair
wiley   +1 more source

Phenotypic characterization and antimicrobial resistance of <i>Campylobacter jejuni</i> and <i>Campylobacter coli</i> in broiler chickens and slaughterhouse workers in Algeria. [PDF]

J Adv Vet Anim Res
Messaoudene H, Guessoum M, Heleili N, Ayachi A.   +3 more
europepmc   +1 more source

Silent pressure: Unveiling spinal lymphoma in horses and its parallels to other species

Equine Veterinary Education, EarlyView.
Summary Though the nervous system is an uncommon location for lymphoma, the disease should remain a differential diagnosis in some cases of ataxia in equids. Diagnosis of lymphoma can be challenging, although a combination of cytology, histopathology and immunophenotyping can aid in definitive diagnosis and therefore more accurately guide treatment and
H. E. Taylor, D. Luethy
wiley   +1 more source

ESBL-producing <i>Escherichia coli</i> in wastewater from German slaughterhouses. [PDF]

One Health
Kleist JF, Bachmann L, Huxdorff C, Eger E, Schaufler K, Wedemeyer J, Homeier-Bachmann T.   +6 more
europepmc   +1 more source

Implicit Promises and the Timing of Defined‐Benefit Pension Plan Freezes

Financial Management, EarlyView.
ABSTRACT Firms time defined‐benefit (DB) plan freezes after CEO turnovers to protect CEO retirement benefits from cost cuts affecting the wider workforce. We document a significant increase in voluntary CEO turnovers just before the freeze, without notable post‐freeze changes.
Zacharias Petrou, Adamos Vlittis
wiley   +1 more source