Results 101 to 110 of about 241,963 (315)

Omics studies: their use in diagnosis and reclassification of SLE and other systemic autoimmune diseases [PDF]

, 2016
María Teruel, Chris Chamberlain, Marta E. Alarcón‐Riquelme   +2 more
openalex   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

The minor allele rs2295613(A), protective against systemic lupus erythematosus, makes a differential contribution to the activity of the SLAMF1 gene promoter in T helpers and in regulatory T lymphocytes

Медицинская иммунология
SLAMF1 (CD150) is a receptor expressed on various hematopoietic cells and involved in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE).
A. N. Uvarova, L. V. Putlyaeva, E. A. Zheremyan, E. M. Stasevich, M. M. Murashko, E. A. Bogomolova, K. V. Korneev, D. E. Demin, A. M. Schwartz, D. V. Kuprash   +9 more
doaj   +1 more source

PTPN22 1858C > T polymorphism and susceptibility to systemic lupus erythematosus: a meta-analysis update

Autoimmunity, 2017
Studies performed in the past years showed PTNP22 1858 C > T (rs2476601) polymorphism as associated with systemic lupus erythematosus susceptibility, although conflicting findings are still found.
Suelen Cristina de Lima, José Eduardo Adelino, Sergio Crovella, Jaqueline de Azevedo Silva, Paula Sandrin-Garcia   +4 more
doaj   +1 more source

Associates and predictors of pleurisy or pericarditis in SLE [PDF]

, 2017
Seungwon Ryu, Wei Fu, Michelle Petri
openalex   +1 more source

Do anti-DFS70 antibodies temper disease activity and progression in SLE? [PDF]

, 2021
May Y. Choi, Ann E. Clarke, Marvin J. Fritzler   +2 more
openalex   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Patients with juvenile idiopathic arthritis (JIA) frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in patients with JIA remains elusive.
Viola Pitkänen, Terhi Remes‐Pakarinen, Paula Vähäsalo, Milja Möttönen, Minna‐Maija Grönlund, Miika Arvonen, Mikael Knip, Riitta Veijola, Jorma Toppari, Jorma Ilonen, Johanna Lempainen, Anna‐Mari Schroderus, Liisa Kröger, Tuure Kinnunen   +13 more
wiley   +1 more source

29 Treatment of CAPS: which drugs and in which order?

Lupus Science and Medicine, 2021
Marc Pineton de Chambrun
doaj   +1 more source