Results 111 to 120 of about 61,448 (241)

Cognitive and behavioral clinical outcome assessments in children with developmental and epileptic encephalopathies: Issues and instruments

open access: yesEpilepsia, EarlyView.
Abstract Children with developmental and epileptic encephalopathies (DEEs) face cognitive and behavioral challenges that may have a greater impact than seizures on their quality of life (QoL). The need to assess these nonseizure outcomes for evaluating treatments is increasingly recognized.
Cinzia Correale   +9 more
wiley   +1 more source

Overlap Syndrome (COPD and OSA): A Treatable Trait for Triple Treatment?

open access: yesPulmonary Therapy
The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in the same patient is referred to as overlap syndrome (OS).
Athanasios Voulgaris   +2 more
doaj   +1 more source

Long‐term prognosis of pharmacotherapy in newly diagnosed focal epilepsy patients and the predictive value of baseline seizure timing: A prospective cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun   +3 more
wiley   +1 more source

Sleep disorders impact hormonal regulation: unravelling the relationship among sleep disorders, hormones and metabolic diseases

open access: yesDiabetology & Metabolic Syndrome
Sleep plays a crucial biological role, and mounting evidence suggests that sleep disorders negatively impact health. In contemporary society, sleep disorders, such as sleep deprivation, insomnia, disrupted sleep-wake disorders, and circadian rhythm ...
Yang Jiao   +8 more
doaj   +1 more source

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

open access: yesEpilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen   +15 more
wiley   +1 more source

Sleep-Wake Disorders

open access: yesJournal of the Royal College of Physicians of London, 1994
openaire   +2 more sources

Are comorbid sleep disorders associated with higher risk for sudden unexpected death in epilepsy? Observations from a Canadian epilepsy clinic

open access: yesEpilepsia, EarlyView.
Abstract Objective Pooled mortality is nearly three times higher in people with epilepsy (PWE). Approximately 80% of sudden unexpected death in epilepsy (SUDEP) events occur during sleep, and primary sleep disorders are prevalent in the general population and PWE.
Marion Lazaj   +7 more
wiley   +1 more source

The effect of in-arms-holding by mothers on sleep-wake states disorders of preterm neonates in neonatal intensive care unit: A pilot study

open access: yesNursing Practice Today, 2015
Background & Aim: Mother-infant separation is one of the main causes of sleep-wake states disorders in neonatal intensive care unit (NICU). The current study was conducted to investigate the effect of in-arms-holding by mothers on sleep-wake states ...
Elaheh Amini   +3 more
doaj  

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