Results 91 to 100 of about 1,833,255 (278)

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

Epilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia, Jina Babanzadeh, Marcello Scala, Lorenzo Perilli, Pasquale Striano   +4 more
wiley   +1 more source

Integrated Analysis of Circadian and Sleep Signatures in Depression and Schizophrenia Using Multi-Day Actigraphy

Bioengineering
Sleep abnormalities and circadian rhythm disruptions are frequently observed in psychiatric disorders such as depression and schizophrenia. However, most previous studies have examined circadian rhythms and sleep separately, limiting understanding of how
Rama Krishna Thelagathoti, Ka-Chun Siu, Hesham H. Ali, Rohan M. Fernando   +3 more
doaj   +1 more source

Circadian Rhythms in the CNS and Peripheral Clock Disorders: Human Sleep Disorders and Clock Genes

Journal of Pharmacological Sciences, 2007
Genetic analyses of circadian rhythm sleep disorders (CRSD), such as familial advanced sleep phase syndrome (ASPS) and delayed sleep phase syndrome (DSPS), and morningness-eveningness revealed the relationship between variations in clock genes and ...
Takashi Ebisawa
doaj   +1 more source

Study of the modulatory mechanism of the miR-182-Clock axis in circadian rhythm disturbance after hypoxic–ischemic brain damage

European Journal of Inflammation, 2020
Hypoxic–ischemic encephalopathy (HIE) in neonates can lead to severe chronic neurological deficit, including mental retardation, epilepsy, and sleep–wake cycle (SWC) disorder.
Dezhan Li, Wei Huang, Fang Yang, Bin Li, Shanshan Cai   +4 more
doaj   +1 more source

Sleep Health in Bulimia Nervosa: A Systematic Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Research on sleep in bulimia nervosa (BN) is methodologically varied and yields inconsistent findings. This review synthesised BN‐sleep studies and examined whether comorbid mood disorders contribute to sleep disturbance. Method PsycINFO, Medline (Ovid), and Scopus were searched for English or French quantitative studies comparing ...
Samantha Kenny, Malka Hershon, Linda Booij, Rebecca Burdayron, Marie‐Hélène Pennestri   +4 more
wiley   +1 more source

Non-24-hour sleep-wake disorder revisited – A case study

Frontiers in Neurology, 2016
The human sleep-wake cycle is governed by two major factors: a homeostatic hourglass process (process S), which rises linearly during the day, and a circadian process C, which determines the timing of sleep in an approximately 24h rhythm in accordance to
Corrado eGarbazza, Vivien eBromundt, Anne eEckert, Daniel P Brunner, Fides eMeier, Sandra eHackethal, Christian eCajochen   +6 more
doaj   +1 more source

Psychopharmacological Prescribing Patterns Among Italian Adolescents With Anorexia Nervosa: Exploring Real‐World Treatment Practices

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To investigate real‐world psychopharmacological prescribing patterns among Italian adolescents with anorexia nervosa (AN) compared with psychiatric controls without eating disorders, and to examine whether AN diagnosis independently predicts medication use after accounting for psychiatric comorbidities.
Marika Orlandi, Arianna Vecchio, Giulia Andorno, Maria Pia Riccio, Cinzia Crispino, Martina Maria Mensi   +5 more
wiley   +1 more source

Monitoring and assessment for obstructive sleep apnea

FlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu, Feifei Lin, Shujiao Chen, Zhen You, Shujing Zhu, Weiwei Zhao, Qiang Zhao   +6 more
wiley   +1 more source

The Association Between Dry Eye and Sleep Disorders: The Evidence and Possible Mechanisms

Nature and Science of Sleep, 2022
Ao Li, Xiaozhao Zhang, Yihan Guo, Jingyi Wang, Yiran Hao, Yixuan Gu, Ying Jie Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Ying Jie, Tel +86-13693572296, Fax +
Li A, Zhang X, Guo Y, Wang J, Hao Y, Gu Y, Jie Y   +6 more
doaj  

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source