Results 101 to 110 of about 63,213 (287)

Reflections On Contributing To “Big Discoveries” About The Fly Clock: Our Fortunate Paths As Post-Docs With 2017 Nobel Laureates Jeff Hall, Michael Rosbash, And Mike Young [PDF]

, 2018
In the early 1980s Jeff Hall and Michael Rosbash at Brandeis University and Mike Young at Rockefeller University set out to isolate the period (per) gene, which was recovered in a revolutionary genetic screen by Ron Konopka and Seymour Benzer for mutants
Hardin, P. E., Price, J. L., Siwicki, Kathleen King   +2 more
core   +4 more sources

Pineal Gland Volume, Sleep Quality, and Psychiatric Disorders: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Disturbances in sleep and circadian rhythms are features of several psychiatric disorders. The pineal gland regulates these rhythms via melatonin, with pineal gland volume (PGV) serving as a structural proxy. We conducted a meta‐analysis to synthesize evidence on differences in PGV between patients with psychiatric disorders and ...
Sophie Bolwig, Kristian H. R. Jensen
wiley   +1 more source

Recent advances in modulators of circadian rhythms: an update and perspective

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Circadian rhythm is a universal life phenomenon that plays an important role in maintaining the multiple physiological functions and regulating the adaptability to internal and external environments of flora and fauna.
Shenzhen Huang, Xinwei Jiao, Dingli Lu, Xiaoting Pei, Di Qi, Zhijie Li   +5 more
doaj   +1 more source

Protocol of the SOMNIA project : an observational study to create a neurophysiological database for advanced clinical sleep monitoring [PDF]

, 2019
Introduction Polysomnography (PSG) is the primary tool for sleep monitoring and the diagnosis of sleep disorders. Recent advances in signal analysis make it possible to reveal more information from this rich data source.
Arsenali, Bruno, Bergmans, Jan W. M., Fonseca, Pedro, Haakma, Reinder, Hoondert, Bertram, Krijn, Roy, Lauwerijssen, Coen, Leufkens, Tim R., Maass, Henning, Overeem, Sebastiaan, Pevernagie, Dirk, Pillen, Sigrid, van den Heuvel, Leonie, van Dijk, Johannes P., van Gilst, Merel M., van Sloun, Ruud J. G., Vandenbussche, Nele   +16 more
core   +2 more sources

Critical care delirium: prevention, identification and management: a narrative review

Anaesthesia, EarlyView.
Summary Introduction Delirium is a frequent complication of critical illness and remains an important cause of short‐ and long‐term morbidity for patients admitted to ICUs. Delirium is associated with prolonged mechanical ventilation; extended ICU and hospital stay; and longer‐term health issues. Development is associated with patient (e.g.
Stephanie Kieswick, Ben Gibbison
wiley   +1 more source

Association of treated neovascular AMD with disability and mood disorders: A longitudinal nationwide study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the associations of treated neovascular AMD with the risk of disability, falls, fractures and mood disorders in a large sample representative of the French population. Methods Analyses were based on 77 582 individuals belonging to the ‘Echantillon Généraliste des Bénéficiaires’, a 1/97 random sample of the French population,
Cécile Delcourt, Emilie Hucteau, Sarra Gattoussi, Karine Pérès, Marie‐Noelle Delyfer, Catherine Helmer, Jean‐François Korobelnik   +6 more
wiley   +1 more source

Long Days Enhance Recognition Memory and Increase Insulin-like Growth Factor 2 in the Hippocampus [PDF]

, 2017
Light improves cognitive function in humans; however, the neurobiological mechanisms underlying positive effects of light remain unclear. One obstacle is that most rodent models have employed lighting conditions that cause cognitive deficits rather than ...
Baker, Kimberly, Callif, Ben L., Dellapolla, Adriano, Evans, Jennifer A., Gilmartin, Marieke R., Hattar, Samer, Hurley, Matthew M., Kloehn, Ian, Pancholi, Harshida, Rohr, Kayla, Wertz, David   +10 more
core   +1 more source

Improving access to help with poor sleep across youth mental health services: Interim implementation and clinical outcomes

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives There is a high, unmet sleep need in young people with mental health difficulties. We took a whole‐system approach to improving access to sleep support across a youth mental health system (14–25 years). Methods We used the Exploration, Preparation, Implementation and Sustainment (EPIS) framework to develop an implementation ...
Rebecca Rollinson, Ben Ewing, Sarah Reeve, Adam Graham, Jonathan Lyons, Brioney Gee, Jonathon Wilson, Ioana Tofan, Kelly Semper, Tim Clarke   +9 more
wiley   +1 more source

Melatonin deficiency and sleep fragmentation in frequent travelers: A modern circadian health crisis

Journal of Education, Health and Sport
Background: Frequent travel disrupts the circadian rhythm, often leading to disturbed melatonin production. This disruption contributes to sleep fragmentation, reduces sleep quality, and cumulative fatigue that many travelers experience as more than ...
Aleksandra Mierniczek, Michalina Chodór, Maciej Kokoszka, Aleksandra Tomaszewska, Kinga Karczewska, Aleksandra Ćwirko-Godycka, Nikola Murawska, Natalia Dymel, Ryszard Feret, Sonia Mojzyk   +9 more
doaj   +1 more source

From barriers to benefits: A personalized sleep intervention enhances sleep duration and emotional health in chronic short sleepers

British Journal of Psychology, EarlyView.
Abstract This pilot study evaluated a personalized sleep intervention incorporating motivational interviewing techniques to address sleep barriers, along with tailored sleep hygiene and extension for chronic short sleepers. Eleven university students completed a 14‐day sequential intervention (baseline, sleep hygiene and a combined phase adding 90‐min ...
Wei Wang, Ho Yin Derek Ma, Ming Ming Chiu, Shu Fai Cheung, C. Harry Hui, Mark Lawrence Wong, Janet Hui‐wen Hsiao, Rong Wei Sun, Yeuk Ching Lam, Akira Basa Okabe, Chin Ho Chan, Esther Yuet Ying Lau   +11 more
wiley   +1 more source