Results 101 to 110 of about 80,932 (340)
StrokeAccumulating evidence supports a link between sleep disorders, disturbed sleep, and adverse brain health, ranging from stroke to subclinical cerebrovascular disease to cognitive outcomes, including the development of Alzheimer disease and Alzheimer ...
Rebecca F Gottesman +10 more
semanticscholar +1 more source
Metabolic alterations in experimental models of depression [PDF]
, 2016 Introduction: Major depressive disorder is one of the most prevalent psychiatric disorders and is associated with a severe impact on the personal functioning, thus with incurring significant direct and indirect costs.
Ionescu, Ecaterina +7 more
core +4 more sources
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Epilepsia Open, EarlyView.Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Blood Pressure Non-Dipping and Obstructive Sleep Apnea Syndrome: A Meta-Analysis [PDF]
, 2019 AIM: We examined the reduced blood pressure (BP) nocturnal fall in patients with obstructive sleep apnea (OSA) by a meta-analysis including studies that provided data on prevalence rates of non-dipping (ND) pattern during 24-h ambulatory blood ...
Cuspidi, Cesare +5 more
core +1 more source
Tea and Blood–Brain Barrier Homeostasis: Potential Mechanisms and Improvement Strategies
Food Frontiers, EarlyView.Abstract The blood–brain barrier (BBB), a selective interface regulating cerebral substance exchange, plays a crucial role in maintaining cognitive function and metabolic balance. While tea consumption has been traditionally associated with health benefits, its specific effects on BBB integrity warrant systematic investigation. This review demonstrates
Rongbosen Yue +5 more
wiley +1 more source
Shift Work: Gut Health and Metabolic Disease [PDF]
, 2020 The number of people engaged in shift work continues to rise, and with it the research linking shift work to various diseases and conditions. Shift work changes the body’s sleeping patterns and circadian rhythms which has an effect on all parts of the ...
Lane, Hailey
core +1 more source
implications for health and disease [PDF]
, 2016 Many aspects of human physiology and behavior display rhythmicity with a period of approximately 24 h. Rhythmic changes are controlled by an endogenous time keeper, the circadian clock, and include sleep-wake cycles, physical and mental performance ...
Heyd, Florian, Preußner, Marco
core +1 more source
Food Safety and Health, EarlyView.Nobiletin (NOB) ameliorates Aβ‐induced Alzheimer’s pathology by restoring circadian rhythm via Bmal1. NOB rescues cognitive deficits, synaptic damage, and mitochondrial dysfunction in mice and neurons by enhancing Bmal1/Clock oscillations and downstream mitochondrial integrity, positioning circadian regulation as a therapeutic target for Alzheimer's ...
Huajing Gao +9 more
wiley +1 more source
The Association Between Dry Eye and Sleep Disorders: The Evidence and Possible Mechanisms
Nature and Science of Sleep, 2022 Ao Li, Xiaozhao Zhang, Yihan Guo, Jingyi Wang, Yiran Hao, Yixuan Gu, Ying Jie Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Ying Jie, Tel +86-13693572296, Fax +
Li A +6 more
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Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults [PDF]
, 2009 This article describes the pharmacology of the novel atypical antidepressant drug agomelatine, critically reviews and evaluates its clinical use for the treatment of major depression, and suggests areas for further research.
Howland, RH
core +1 more source