Results 201 to 210 of about 63,213 (287)

Characterizing circadian rest–activity rhythm patterns across Alzheimer's disease continuum in Down syndrome

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Sleep and circadian rest–activity rhythm (RAR) disruption may bidirectionally relate to Alzheimer's disease (AD). Down syndrome (DS), the most common genetic cause of AD, presents sleep disorders, yet RAR patterns across the DS‐associated AD continuum remain uncharacterized. METHODS We analyzed 7‐day wrist actigraphy in 140 adults
Sandra Giménez   +26 more
wiley   +1 more source

One Eye Open: Reflections on Embedding Lived Experience in Sleep, Circadian Rhythms, and Mood Disorder Research. [PDF]

open access: yesHealth Expect
Hockey SJ   +11 more
europepmc   +1 more source

Associations of sleep behaviors with white matter hyperintensity volume in middle‐aged to older adults

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Poor sleep has been associated with elevated dementia risk, potentially related to its cerebrovascular consequences, measured by cerebral white matter hyperintensity (WMH) volume. METHODS We examined self‐reported sleep behaviors and prospective magnetic resonance imaging (MRI) WMH volume, measured 8.8 ± 1.7 (mean ± SD) years ...
Madeline Ally   +10 more
wiley   +1 more source

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individuals

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1473-1486, May 2026.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia   +3 more
wiley   +1 more source

The Correlations and Predictive Capabilities of the “Life's Essential 8” With Respect to All‐Cause Mortality and Cardiovascular Disease Mortality Risks in Individuals Experiencing Sleep Disorders: A Prospective Cohort Study From the NHANES (2005–2014)

open access: yesClinical Cardiology, Volume 49, Issue 5, May 2026.
The study shows the inverse correlation between Life's Essential 8 (LE8) scores and the risks of all‐cause and cardiovascular disease (CVD) mortality among patients with sleep disorders using data from NHANES 2005–2014. ABSTRACT Background Life's Essential 8 (LE8) is a framework for assessing cardiovascular health (CVH).
Jia Wei   +7 more
wiley   +1 more source

Chronotype and its Association With Weight Status and Dietary Patterns Among Tunisian Female University Students. [PDF]

open access: yesAm J Lifestyle Med
Jemai C   +9 more
europepmc   +1 more source

Hair Cortisol Concentrations in Children: A Longitudinal Analysis Across Childhood

open access: yesDevelopmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Hair cortisol concentration (HCC) reflects long‐term cortisol exposure and is commonly used as a biomarker of hypothalamic–pituitary–adrenal axis activity. Although increasingly applied in pediatric populations, developmental changes in HCC and potential sex differences remain unclear.
Miguel Ángel Baos‐González   +4 more
wiley   +1 more source

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