Associated factors and a risk prediction model for comorbid circadian rhythm sleep-wake disorders in patients with chronic fatigue syndrome: implications for early screening and sleep health management. [PDF]
Shao X +10 more
europepmc +1 more source
ABSTRACT Physical activity (PA) is frequently promoted as a means of managing symptoms associated with the menopause transition (MT), yet little is known of how the embodied, emotional and temporal disruptions of menopause influence the experiences of, and possibilities for, movement.
Cassandra Phoenix +2 more
wiley +1 more source
Suicide and Sleep Disorders: The Role of Insomnia, Nightmares, and Circadian Disruption. [PDF]
Debellotte O +9 more
europepmc +1 more source
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle +7 more
wiley +1 more source
Biological and Habitual Factors That Influence Sleep and Circadian Rhythm: A Narrative Review. [PDF]
Harmon VJ, Davis CJ.
europepmc +1 more source
Melatonin Levels in 89 Individuals With Smith Magenis Syndrome
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley +1 more source
MELODY trial: study protocol for a 12-week randomised controlled trial of adjunctive melatonin, digital cognitive behavioural therapy for insomnia or pill placebo to improve depressive symptoms in young adults with mood disorders. [PDF]
Crouse JJ +28 more
europepmc +1 more source
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc +7 more
wiley +1 more source
Circadian-immune crosstalk in insomnia disorder: mechanisms and therapeutic implications. [PDF]
Huang Y, Wang X, Chen X, Liu Y.
europepmc +1 more source
Brewing Anxiety: Caffeine‐Induced Thigmotaxis in Zebrafish Larvae
ABSTRACT Background Thigmotaxis, or edge preference, is widely used as a measure of anxiety in vertebrate model systems. However, variability in this behavior limits its utility as a scalable measure for anxiolytic drug discovery. In the current study, we examine caffeine‐induced thigmotaxis, using 5‐day‐old zebrafish larvae as a model system.
Rishi Rai +2 more
wiley +1 more source

