Results 221 to 230 of about 62,872 (285)

Circadian clock genes and insomnia: molecular mechanisms and therapeutic implications. [PDF]

Ann Med
Ren Q, Gu M, Fan X.
europepmc   +1 more source

Exogenous Melatonin and Sleep Quality: A Scoping Review of Systematic Reviews

The Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.
Abstract Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta‐analyses assessing the effects of exogenously administered melatonin on sleep quality in humans.
Samyuktha Iyer, Vaneesha Monk, Rebeccah Slater, Luke Baxter   +3 more
wiley   +1 more source

Pathophysiological mechanisms of functional dyspepsia: a narrative review. [PDF]

Front Med (Lausanne)
Wang L, Shi Y, Li Y, Wang X, Xu L, Zhang Y.   +5 more
europepmc   +1 more source

The Ontogenetic Development of Rapid Eye Movement Sleep in Early Life and Its Regulatory Mechanisms

International Journal of Developmental Neuroscience, Volume 86, Issue 1, February 2026.
REM sleep was first identified in humans and cats in the late 1950s and exhibits a conserved developmental trajectory across species. This study elucidates key characteristic changes during REM sleep development, thereby providing a foundation for improving the prevention and treatment of various neurodevelopmental disorders.
Xiu‐Juan Zhang, Xu‐Hao Gao, An‐Hong Wang, Cai‐Qin Wang, Jia Liu, Yan‐Li Hu, Bo‐Wen Duan, Hai‐Yun Huang, Jin‐Xian Gao   +8 more
wiley   +1 more source

Associations between sleep and circadian rhythm disruption and perinatal anxiety. [PDF]

NPJ Biol Timing Sleep
Cox RC.
europepmc   +1 more source

Longan flower water extract promotes sleep in mice via the serotonin–melatonin axis

Journal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1852-1860, February 2026.
Abstract BACKGROUND Longan (Dimocarpus longan) flower is an underutilized botanical byproduct rich in polyphenols with reported neuroprotective actions, yet its role in sleep regulation remains unclear. This study aimed to evaluate the sleep‐promoting effects of longan flower water extract (LFWE) and its underlying neurochemical mechanisms in vivo ...
Tzu‐Huan Hung, Chiu‐Ping Cheng, Wei‐Chung Chiou, Tzu‐Lan Hsia, Hui‐Kang Liu, Hsu‐Feng Lu, Yu‐Heng Lai, Shang‐Ting Tsai, Chiung‐Ju Chen, Cheng Huang   +9 more
wiley   +1 more source

Bidirectional crosstalk between sleep disorders and gynecological cancers: unraveling molecular synergies and precision therapeutics. [PDF]

Front Med (Lausanne)
Mei H, Zhao C, Jin H, Qi W, Lu X, Xin Y, Wang W, Sun Y, Li WY.   +8 more
europepmc   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

ADHD as a circadian rhythm disorder: evidence and implications for chronotherapy. [PDF]

Front Psychiatry
Luu B, Fabiano N.
europepmc   +1 more source

The Impact of Baseline Sleep as a Potential Moderator of Weight Loss Intervention in Breast Cancer Survivors: Results From the POWER‐Remote Trial

Obesity, Volume 34, Issue 2, Page 334-343, February 2026.
ABSTRACT Objective We evaluated whether sleep disturbance moderates weight loss in breast cancer survivors. We hypothesized that poor sleep prior to behavioral weight loss (BWL) would be associated with less weight reduction than better sleep. Methods Women with prior stage 0‐III breast cancer with BMI ≥ 25 kg/m2 were randomized to BWL (n = 47) or self‐
Jennifer Y. Sheng, Ruizhe Chen, Gary L. Rosner, Claire F. Snyder, Lawrence J. Appel, Vered Stearns, Michael T. Smith, Janelle W. Coughlin   +7 more
wiley   +1 more source