Results 121 to 130 of about 283,220 (362)

Traumatic Brain Injury and Disturbed Sleep and Wakefulness [PDF]

, 2018
Traumatic brain injury is a frequent condition worldwide, and sleep-wake disturbances often complicate the course after the injuring event. Current evidence suggests that the most common sleep-wake disturbances following traumatic brain injury include ...
Baumann, Christian
core  

In search of sleep biomarkers of Alzheimer's disease: K-Complexes do not discriminate between patients with mild cognitive impairment and healthy controls [PDF]

, 2017
The K-complex (KC) is one of the hallmarks of Non-Rapid Eye Movement (NREM) sleep. Recent observations point to a drastic decrease of spontaneous KCs in Alzheimer's disease (AD).
Cordone, Susanna, D\u2019Atri, Aurora, De Gennaro, Luigi, Ferrara, Michele, Gorgoni, Maurizio, Lacidogna, Giordano, Lauri, Giulia, Mangiaruga, Anastasia, Marra, Camillo (ORCID:0000-0003-3994-4044), Reda, Flaminia, Rossini, Paolo Maria (ORCID:0000-0003-2665-534X), Scarpelli, Serena, Truglia, Ilaria   +12 more
core   +2 more sources

Integrating Astrocytes in the Sleep–Wake Cycle: The Time Is Now

BioEssays, EarlyView.
Astrocytes actively regulate sleep homeostatic and circadian rheostatic processes, underpinning the sleep–wake cycle. By acting as context‐dependent integrators of internal state and rhythmic environmental inputs, they modulate the encoding properties of neuronal circuitries and contribute to salient temporal representations in the brain.
Marco Brancaccio
wiley   +1 more source

A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait. [PDF]

, 2016
In humans, the connection between sleep and mood has long been recognized, although direct molecular evidence is lacking. We identified two rare variants in the circadian clock gene PERIOD3 (PER3-P415A/H417R) in humans with familial advanced sleep phase ...
Fu, Ying-Hui, Hirano, Arisa, Hsu, Pei-Ken, Jones, Christopher R, Kaasik, Krista, Lin, Shu-Ting, McMahon, Thomas, Nishino, Seiji, Okuro, Masashi, Ptáček, Louis J, Saigoh, Kazumasa, Saigoh, Noriko, Sakai, Noriaki, Xu, Ying, Yamazaki, Maya, Zhang, Luoying   +15 more
core   +1 more source

Targeting Cryptochromes in Chronic Diseases

Cell Biology International, EarlyView.
ABSTRACT The circadian clock generates 24‐h molecular rhythms through transcription–translation negative feedback loops (TTFLs) and regulates daily physiological processes such as sleep–wake cycles, body temperature, hormone secretion, metabolism, and immune function.
Takuro Toda, Tsuyoshi Hirota
wiley   +1 more source

Feasibility and Acceptability of Brief Behavioral Treatment for Insomnia After Eating Disorder Treatment: The TIRED Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The purpose of this pilot trial was to evaluate the novel use of Brief Behavioral Treatment for Insomnia (BBTI) for people with residual insomnia disorder following eating disorder (ED) treatment. Methods Participants (N = 6) completed a multiple‐baseline design study of BBTI.
Kara A. Christensen Pacella, Angeline R. Bottera, Kelsie T. Forbush, Jaelin Isquith, Kyle De Young   +4 more
wiley   +1 more source

Delayed sleep-wake phase disorder [PDF]

Journal of Thoracic Disease, 2018
Delayed sleep-wake phase disorder (DSWPD) is the most commonly encountered of the circadian rhythm sleep-wake disorders (CRSDs), and is often confused with sleep initiation insomnia. It typically emerges in teenage years and persists into adulthood. In essence, people with the disorder have an abnormally delayed major sleep episode relative to the dark
openaire   +3 more sources

Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnosis in the neonatal period, infancy, childhood and adolescence, and review of the literature

Epileptic Disorders, EarlyView.
Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor, S. Sharma, A. Kaminska, R. Nabbout, N. Chemaly, M. Schiff, P. De Lonlay, M. Eisermann   +7 more
wiley   +1 more source

Current Considerations in the Diagnosis and Treatment of Circadian Rhythm Sleep-Wake Disorders in Children. [PDF]

Semin Pediatr Neurol, 2023
Witt RM, Byars KC, Decker K, Dye TJ, Riley JM, Simmons D, Smith DF.   +6 more
europepmc   +1 more source

Therapeutic progress of two sibling cases exhibiting sleep–wake rhythm disorder [PDF]

, 2000
Masaki Mukai, Naohisa Uchimura, Noboru Takeuchi, Yoshifumi Waseda, Junko Takaishi, Tetsuro Sakamoto, Hisao Maeda   +6 more
openalex   +1 more source