Results 181 to 190 of about 75,467 (306)

Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease

open access: yesNeuroprotection, EarlyView.
Early disease stages showed limited cortical atrophy and enrichment of synaptic and calcium signaling pathways, whereas advanced stages demonstrated widespread cortical degeneration associated with immune activation and extracellular matrix remodeling.
Yi Ji   +6 more
wiley   +1 more source

Impact of Preoperative Daytime Sleepiness and Insomnia on Therapy Adherence and Neurostimulation Amplitude in Unilateral Hypoglossal Nerve Stimulation

open access: yes
Johannes Pordzik,1,* Katharina Ludwig,1,* Christian Ruckes,2 Haralampos Gouveris1 1Department of Otolaryngology/Head and Neck Surgery & Sleep Medicine Center, University Medical Center Mainz, Mainz, 55131, Germany; 2Interdisciplinary Center for ...
Ludwig K   +3 more
core  

On the botanical history and nomenclature of the New World genus Piscidia (Fabaceae)

open access: yesNordic Journal of Botany, EarlyView.
Piscidia L. (Fabaceae) is a New World genus with nine recognized taxa (seven species and two varieties). The previous nomenclatural revisions, made in 1910 and in 1969, are revisited here. The names Derris grandifolia Heyde & Lux ex Donn.Sm. and P. cubensis Urb. required step II lectotypifications, with an epitype for the latter name.
Camila Sánchez‐ Vega   +4 more
wiley   +1 more source

Codeine and Metabolite Concentrations in the Breastfed Neonate

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Analgesic effect from codeine is from its metabolite, morphine. Morphine is formed by the O‐demethylation of codeine and that enzyme is controlled by the cytochrome P450 2D6. More than 60 alleles in the CYP2D6 gene have been identified. This spectrum of polymorphism can be categorized into four groups: poor (PM), intermediate (IM), normal (NM),
Brian J. Anderson, Jacqueline A. Hannam
wiley   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale   +4 more
wiley   +1 more source

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco   +5 more
wiley   +1 more source

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