Results 111 to 120 of about 920,377 (338)

Law of Friction: from Tribology to Tribo-Fatigue. Report 2. Theoretical Studies

Механика машин, механизмов и материалов, 2019
To date, many laws of Nature have been discovered. The knowledge of each of them led to the accelerated development of the relevant sections of science and further, as a rule, to progress in any practical area of the community of people.
Leonid A. Sosnovskiy
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Surface heat transfer due to sliding bubble motion [PDF]

, 2009
The presence of a rising bubble in a fluid can greatly enhance heat transfer from adjacent heated surfaces such as in shell and tube heat exchangers and chemical reactors.
Tadhg S. O’Donovan, Murray, Darina B., Darina B. Murray, O'Donovan, Tadhg S., Brian Donnelly, O'Donovan, Tadhg S.; id_orcid, Donnelly, Brian   +6 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Prediction of Sliding Wear of Artificial Rough Surfaces [PDF]

, 2012
When two surfaces are brought in contact, deformation takes place at asperity level. The local pressure distribution and deformation of the contacting surfaces are importance with respect to wear.
Imam , Syafa’at, J. , Jamari, Rifky , Ismail, Budi , Setiyana, Eko , Saputra, D.J., Schipper   +5 more
core   +1 more source

Adherence between steel bars and lightweight concrete with EPS beads

Revista IBRACON de Estruturas e Materiais
This paper describes the adherence behavior of a structural lightweight concrete with EPS beads (SLCEB) in a monotonic loading, based in a bibliographic review and in pull-out tests.
A. L. SARTORI, L. M. PINHEIRO, R. M. DA SILVA, S. B. FREITAS, T. G. CESAR   +4 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A unified control strategy based on precise feedback linearization and sliding mode for DC-APF in DC current ripple suppression

Frontiers in Energy Research
In the current power system, the conversion between DC and AC is widespread, and the DC-side harmonic problem is prominent. A DC Active Power Filter (DC-APF) is a good solution for suppressing low-frequency current ripples.
Peng Ren, Ping Liu, Chuanchuan Hou, Zhi Zhou, Xueping Yu   +4 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source