Results 51 to 60 of about 920,377 (338)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Robust H-infinity sliding mode control for nonlinear stochastic systems with multiple data packet losses [PDF]

, 2012
This is the post-print version of this Article. The official published version can be accessed from the link below - Copyright @ 2012 John Wiley & SonsIn this paper, an ∞ sliding mode control (SMC) problem is studied for a class of discrete-time ...
Wang, Z, Ma, L, Bo, Y, Guo, Z
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

FRICTION COEFFICIENT BETWEEN SOCCER BALL AND GOALKEEPER GLOVE [PDF]

Journal of the Egyptian Society of Tribology, 2019
The present work investigates the influence of friction coefficient of the outer layer of the goalkeeper gloves on the ability to catch or punch the soccer ball.
A. M. Samy, W. Y. Ali
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Decentralised sliding mode control for a class of nonlinear interconnected systems [PDF]

, 2015
In this paper, a decentralised control strategy based on sliding mode techniques is proposed for a class of nonlinear interconnected systems. Both matched uncertainties in the isolated subsystems and mismatched uncertainties associated with the ...
Sarah K. Spurgeon, Mu, Jianqiu, Yan, Xinggang, Spurgeon, Sarah K., Jianqiu Mu, Xing-Gang Yan   +5 more
core   +1 more source

INCREASING FRICTION COEFFICIENT DISPLAYED BY SLIDING BETWEEN THE FOOTBALL AND THE GLOVES OF THE GOALKEEPER [PDF]

Journal of the Egyptian Society of Tribology, 2019
The present work aims to investigate the friction coefficient between different gloves and football surfaces in order to provide a suitable high friction and safe coating surface for goalkeeper gloves.
Y. M. Youssef, M. I. Khashaba, W. Y. Ali
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Spectral roughness of glaciated bedrock geomorphic surfaces: Implications for glacier sliding [PDF]

, 2000
A microroughness meter (MRM) was used to measure the high-frequency roughness of a number of geomorphic surfaces in the forefield of Glacier de Tsanfleuron, Switzerland.
Martin J. Siegert, Danny McCarroll, Hubbard, B., McCarroll, D., Bryn Hubbard, Siegert, M. J.   +5 more
core   +1 more source

Law of Friction: from Tribology to Tribo-Fatigue. Report 1. Classical Law of (Dry) Friction and Need for its Adjustment

Механика машин, механизмов и материалов, 2019
To date, many laws of Nature have been discovered. The knowledge of each of them led to the accelerated development of the relevant sections of Science and further, as a rule, to progress in any practical area of the community of people. The empirical
Leonid A. Sosnovskiy
doaj