Results 71 to 80 of about 920,377 (338)

Continuous Nearest Neighbor Queries over Sliding Windows [PDF]

open access: yes, 2007
—This paper studies continuous monitoring of nearest neighbor (NN) queries over sliding window streams. According to this model, data points continuously stream in the system, and they are considered valid only while they belong to a sliding window that ...
Papadias, Dimitris   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Arnol′d tongues arising from a grazing-sliding bifurcation [PDF]

open access: yes, 2009
The Neımark–Sacker bifurcation, or Hopf bifurcation for maps, is a well-known bifurcation for smooth dynamical systems. At this bifurcation a periodic orbit loses stability, and, except at certain “strong” resonances, an invariant torus is born.
Osinga, HM   +3 more
core   +1 more source

Sliding hernia uterus inguinale in a child

open access: yesSaudi Journal for Health Sciences, 2018
Uterine adnexa may be the content of the inguinal hernial sac in up to one-fifth of the pediatric female patients. Inguinal hernia containing uterus is known as “hernia uterus inguinale” which is a very rare condition.
Rahul Gupta
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Sliding bifurcations and non-determinism in systems with switching [PDF]

open access: yes, 2011
Dynamical events associated with loss of determinacy in piecewise-smooth dynamical systems are reviewed. The causes of non-determinacy are discussed, and the conditions for their occurence in general systems are derived. These events can be characterized
Mike R Jeffrey, Jeffrey, Mike R
core   +1 more source

Understanding the friction laws of Amontons and Coulomb by evaluating the real contact area

open access: yesFriction
Friction is a complex phenomenon that depends on many parameters. Despite this, we still rely on and describe friction in the vast majority of cases with a single value, namely, the coefficient of friction (µ), as first proposed by Amontons in 1699 ...
Mitjan Kalin, Petra Jan
doaj   +1 more source

Evaluation of the effect of different points of orthodontic force application (A typodont study) [PDF]

open access: yesAl-Rafidain Dental Journal, 2011
Aims: To determine the effect of different points of force application on dimensional positions and the ratio of space closure of maxillary canine using sliding mechanics.
Omar KhM Thiab   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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