Results 61 to 70 of about 323,696 (314)

'Calving laws', 'sliding laws' and the stability of tidewater glaciers [PDF]

, 2007
A new calving criterion is introduced, which predicts calving where the depth of surface crevasses equals ice height above sea level. Crevasse depth is calculated from strain rates, and terminus position and calving rate are therefore functions of ice ...
Hulton, N R J, Mottram, Ruth H., Benn, Douglas Iain, Mottram, R H, Hulton, Nicholas R. J., Benn, Douglas I.   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Skyhook surface sliding mode control on semi-active vehicle suspension systems for ride comfort enhancement [PDF]

, 2009
A skyhook surface sliding mode control method was proposed and applied to the control on the semi-active vehicle suspension system for its ride comfort enhancement.
Yi Chen, Chen, Y.
core   +1 more source

Dynamic Response of Ancient Dowel-Connected Multi-Drum Columns: A 3D Finite Element Study of Friction Effects

Buildings
The dynamic response of ancient multi-drum columns, commonly found in historical monuments, is characterized by complex nonlinear mechanisms including rocking, sliding, and wobbling.
Olympia K. Panagouli, Maria Kafetsi
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Sliding hernia uterus inguinale in a child

Saudi Journal for Health Sciences, 2018
Uterine adnexa may be the content of the inguinal hernial sac in up to one-fifth of the pediatric female patients. Inguinal hernia containing uterus is known as “hernia uterus inguinale” which is a very rare condition.
Rahul Gupta
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Understanding the friction laws of Amontons and Coulomb by evaluating the real contact area

Friction
Friction is a complex phenomenon that depends on many parameters. Despite this, we still rely on and describe friction in the vast majority of cases with a single value, namely, the coefficient of friction (µ), as first proposed by Amontons in 1699 ...
Mitjan Kalin, Petra Jan
doaj   +1 more source

Evaluation of the effect of different points of orthodontic force application (A typodont study) [PDF]

Al-Rafidain Dental Journal, 2011
Aims: To determine the effect of different points of force application on dimensional positions and the ratio of space closure of maxillary canine using sliding mechanics.
Omar KhM Thiab, Ahmed A Abdul– Mawjood, Ahmed Gh Mohammed   +2 more
doaj   +1 more source